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Relationship of salusin-alpha and salusin-beta levels with atherosclerosis in patients undergoing haemodialysis

   Sipahi, Savas; Genc, Ahmed Bilal; Acikgoz, Seyyid Bilal; Yildirim, Mehmet; Aksoy, Yakup Ersel; Vatan, Mehmet Bulent; Dheir, Hamad; Altindis, Mustafa

INTRODUCTION In patients undergoing haemodialysis, cardiovascular mortality and morbidity, characterised by accelerated atherosclerosis and increased inflammation, are elevated. Salusins are newly defined molecules in the atherosclerotic processes, and while salusin-alpha (Sal-alpha) acts as an antiatherogenic factor, salusin-beta (Sal-beta) has a proatherogenic role. Their roles are as yet undefined in patients undergoing haemodialysis.

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