1 Ocak 2016 Dergi makalesi Açık Erişim

Kiraz, Yagmur; Baran, Yusuf; Nalbant, Ayten

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/60673</identifier>
  <creators>
    <creator>
      <creatorName>Kiraz, Yagmur</creatorName>
      <givenName>Yagmur</givenName>
      <familyName>Kiraz</familyName>
    </creator>
    <creator>
      <creatorName>Baran, Yusuf</creatorName>
      <givenName>Yusuf</givenName>
      <familyName>Baran</familyName>
    </creator>
    <creator>
      <creatorName>Nalbant, Ayten</creatorName>
      <givenName>Ayten</givenName>
      <familyName>Nalbant</familyName>
      <affiliation>Izmir Inst Technol, Mol Immunol &amp; Gene Regulat Lab, Dept Mol Biol &amp; Genet, TR-35430 Izmir, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>T Cells In Tumor Microenvironment</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2016</publicationYear>
  <dates>
    <date dateType="Issued">2016-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/60673</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1007/s13277-015-4241-1</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
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  <descriptions>
    <description descriptionType="Abstract">Tumors progress in a specific area, which supports its development, spreading or shrinking in time with the presence of different factors that effect the fate of the cancer cells. This specialized site is called "tumor microenvironment" and has a composition of heterogenous materials. The immune cells are also residents of this stromal, cancerous, and inflammatory environment, and their types, densities, or functional differences are one of the key factors that mediate the fate of a tumor. T cells as a vital part of the immune system also are a component of tumor microenvironment, and their roles have been elucidated in many studies. In this review, we focused on the immune system components by focusing on T cells and detailed T helper cell subsets in tumor microenvironment and how their behaviors affect either the tumor or the patient's outcome.</description>
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