1 Ocak 2016 Dergi makalesi Açık Erişim

Coskun, Abdurrahman; Baykal, Ahmet Tarik; Kazan, Dilek; Akgoz, Muslum; Senal, Merve Oztug; Berber, Ibrahim; Titiz, Izzet; Bilsel, Gokhan; Kilercik, Hakan; Karaosmanoglu, Kubra; Cicek, Muslum; Yurtsever, Ilknur; Yazici, Cevat

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{
  "@context": "https://schema.org/", 
  "@id": 60293, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Acibadem Univ, Sch Med, Dept Med Biochem, Istanbul, Turkey", 
      "name": "Coskun, Abdurrahman"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Acibadem Univ, Sch Med, Dept Med Biochem, Istanbul, Turkey", 
      "name": "Baykal, Ahmet Tarik"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Marmara Univ, Fac Engn, Dept Bioengn, Istanbul, Turkey", 
      "name": "Kazan, Dilek"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Natl Metrol Inst, Gebze, Turkey", 
      "name": "Akgoz, Muslum"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Natl Metrol Inst, Gebze, Turkey", 
      "name": "Senal, Merve Oztug"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Acibadem Univ, Sch Med, Dept Gen Surg, Istanbul, Turkey", 
      "name": "Berber, Ibrahim"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Haydarpasa Numune Res & Training Hosp, Dept Gen Surg, Istanbul, Turkey", 
      "name": "Titiz, Izzet"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Natl Metrol Inst, Gebze, Turkey", 
      "name": "Bilsel, Gokhan"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Yeni Yuzyil Univ, Gaziosmanpasa Hosp, Dept Anesthesiol, Istanbul, Turkey", 
      "name": "Kilercik, Hakan"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Marmara Univ, Fac Engn, Dept Bioengn, Istanbul, Turkey", 
      "name": "Karaosmanoglu, Kubra"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Yeni Yuzyil Univ, Gaziosmanpasa Hosp, Dept Anesthesiol, Istanbul, Turkey", 
      "name": "Cicek, Muslum"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Istanbul Medipol Univ, Regenerat & Restorat Med Res Ctr, Beykoz Istanbul, Turkey", 
      "name": "Yurtsever, Ilknur"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Erciyes Univ, Sch Med, Dept Med Biochem, Kayseri, Turkey", 
      "name": "Yazici, Cevat"
    }
  ], 
  "datePublished": "2016-01-01", 
  "description": "One of the main issues in kidney transplantation is the optimal functional preservation of the organ until its transplantation into the appropriate recipient. Despite intensive efforts, the functional preservation period remains limited to hours. During this time, as a result of cellular injury, various proteins, peptides, and other molecules are released by the organ into the preservation medium. In this study, we used proteomic techniques to analyze the protein profiles of preservation solutions in which organs had been preserved prior to their transplantation. Samples were obtained from the preservation solutions of 25 deceased donor kidneys scheduled for transplantation. The protein profiles of the solutions were analyzed using 2D gel electrophoresis/MALDI-TOF and LC-MS/MS. We identified and quantified 206 proteins and peptides belonging to 139 different groups. Of these, 111 proteins groups were belonging to kidney tissues. This study used proteomic techniques to analyze the protein profiles of organ preservation solutions. These findings will contribute to the development of improved preservation solutions to effectively protect organs for transplantation.", 
  "headline": "Proteomic Analysis of Kidney Preservation Solutions Prior to Renal Transplantation", 
  "identifier": 60293, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Proteomic Analysis of Kidney Preservation Solutions Prior to Renal Transplantation", 
  "url": "https://aperta.ulakbim.gov.tr/record/60293"
}