1 Ocak 2016 Dergi makalesi Açık Erişim

Kocak, Emrah; Saglam, Mehmet; Kayis, Seyit Ali; Dundar, Niyazi; Kebapcilar, Levent; Loos, Bruno G.; Hakki, Sema S.

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<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Kocak, Emrah</dc:creator>
  <dc:creator>Saglam, Mehmet</dc:creator>
  <dc:creator>Kayis, Seyit Ali</dc:creator>
  <dc:creator>Dundar, Niyazi</dc:creator>
  <dc:creator>Kebapcilar, Levent</dc:creator>
  <dc:creator>Loos, Bruno G.</dc:creator>
  <dc:creator>Hakki, Sema S.</dc:creator>
  <dc:date>2016-01-01</dc:date>
  <dc:description>In order to evaluate whether nonsurgical periodontal treatment with/without diode laser (DL) decontamination improves clinical parameters, the levels of IL-1 beta, IL-6, IL-8, intercellular adhesion molecule (ICAM), and vascular cell adhesion molecule (VCAM) in gingival crevicular fluid and metabolic control (HbA1c) in chronic periodontitis (CP) patients with diabetes mellitus type 2 (DM2). Sixty patients with DM2 and CP were randomly assigned into two groups to receive scaling and root planing (SRP, n = 30) or SRP followed by diode laser application (SRP + DL, n = 30). Clinical periodontal and gingival crevicular fluid (GCF) parameters were assessed at baseline, 1, and 3 months after periodontal treatment. HbA1c levels were evaluated at baseline and 3 months post-therapy. Total amounts of cytokines and molecules were analyzed by ELISA. Nonsurgical periodontal treatment with/without DL appeared to improve clinical, biochemical parameters, and glycemic control in DM2 patients (BMI &lt; 25 kg/m(2)) with CP. The SRP + DL group provided better reductions in probing depth (PD) and clinical attachment level (CAL) parameters compared to the SRP group (P &lt; 0.05). Significant reductions were found in the total amounts of GCF levels of IL-1, IL-6, IL-8, ICAM, and VCAM after treatment (P &lt; 0.05). HbA1c levels decreased significantly at 3 months after treatment (P &lt; 0.05). SRP + DL reduced HbA1c levels more significantly compared to SRP alone (0.41 vs. 0.22 %, P &lt; 0.05). SRP, especially in combination with DL, shows improvement of glycemic control for DM2 patients with CP.</dc:description>
  <dc:identifier>https://aperta.ulakbim.gov.trrecord/59629</dc:identifier>
  <dc:identifier>oai:zenodo.org:59629</dc:identifier>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>http://www.opendefinition.org/licenses/cc-by</dc:rights>
  <dc:source>LASERS IN MEDICAL SCIENCE 31(2) 343-353</dc:source>
  <dc:title>Nonsurgical periodontal therapy with/without diode laser modulates metabolic control of type 2 diabetics with periodontitis: a randomized clinical trial</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
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