1 Ocak 2016 Dergi makalesi Açık Erişim

Yeung, Timothy W.; Ucok, Elif F.; Tiani, Kendra A.; McClements, David J.; Sela, David A.

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{
  "@context": "https://schema.org/", 
  "@id": 58865, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Univ Massachusetts, Dept Food Sci, Amherst, MA 01003 USA", 
      "name": "Yeung, Timothy W."
    }, 
    {
      "@type": "Person", 
      "affiliation": "Univ Massachusetts, Dept Food Sci, Amherst, MA 01003 USA", 
      "name": "Ucok, Elif F."
    }, 
    {
      "@type": "Person", 
      "name": "Tiani, Kendra A."
    }, 
    {
      "@type": "Person", 
      "name": "McClements, David J."
    }, 
    {
      "@type": "Person", 
      "name": "Sela, David A."
    }
  ], 
  "datePublished": "2016-01-01", 
  "description": "Probiotic microorganisms are incorporated into a wide variety of foods, supplements, and pharmaceuticals to promote human health and wellness. However, maintaining bacterial cell viability during storage and gastrointestinal transit remains a challenge. Encapsulation of bifidobacteria within food-grade hydrogel particles potentially mitigates their sensitivity to environmental stresses. In this study, Bifidobacterium longum subspecies and strains were encapsulated in core-shell microgels consisting of an alginate core and a microgel shell. Encapsulated obligate anaerobes Bifidobacterium longum subsp. infantis and Bifidobacterium longum subsp. Iongum exhibited differences in viability in a strain-dependent manner, without a discernable relationship to subspecies lineage. This includes viability under aerobic storage conditions and modeled gastrointestinal tract conditions. Coating alginate microgels with chitosan did not improve viability compared to cells encapsulated in alginate microgels alone, suggesting that modifying the surface charge alone does not enhance delivery. Thus hydrogel beads have great potential for improving the stability and efficacy of bifidobacterial probiotics in various nutritional interventions.", 
  "headline": "Microencapsulation in Alginate and Chitosan Microgels to Enhance Viability of Bifidobacterium longum for Oral Delivery", 
  "identifier": 58865, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Microencapsulation in Alginate and Chitosan Microgels to Enhance Viability of Bifidobacterium longum for Oral Delivery", 
  "url": "https://aperta.ulakbim.gov.tr/record/58865"
}