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Synthesis and cytotoxic activities of novel 2-(1,5-bis(aryl) penta-1,4-dien-2-yl) benzo[d]thiazol derivatives

Sahin, Betul; Yaglioglu, Ayse Sahin; Ceylan, Mustafa


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{
  "@context": "https://schema.org/", 
  "@id": 55717, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Gaziosmanpasa Univ, Fac Art & Sci, Dept Chem, TR-60250 Tokat, Turkey", 
      "name": "Sahin, Betul"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Cankiri Karatekin Univ, Fac Sci, Dept Chem, TR-18100 Cankiri, Turkey", 
      "name": "Yaglioglu, Ayse Sahin"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Gaziosmanpasa Univ, Fac Art & Sci, Dept Chem, TR-60250 Tokat, Turkey", 
      "name": "Ceylan, Mustafa"
    }
  ], 
  "datePublished": "2016-01-01", 
  "description": "Novel 2-(1,5-bis(aryl) penta-1,4-dien-2-yl) benzo[d] thiazol (5a,b) and 2-(((1S,2S,E)-2(benzo[d] thiazol-2-yl)-1,5-di-arylpent-4-en-1-yl) thio) aniline (6a, b) derivatives were obtained by addition of 2aminobenzothiol to bis-benzylidinecyclobutanones (3a,b). The structures of the obtained compounds were characterized using the spectroscopic methods (NMR, IR, Elemental Analysis). Compounds 5a,b showed cytotoxic activities against C6 (Rat Brain tumor cells) and HeLa (human uterus carcinoma) in vitro. (C) 2016 ACG Publications. All rights reserved.", 
  "headline": "Synthesis and cytotoxic activities of novel 2-(1,5-bis(aryl) penta-1,4-dien-2-yl) benzo[d]thiazol derivatives", 
  "identifier": 55717, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Synthesis and cytotoxic activities of novel 2-(1,5-bis(aryl) penta-1,4-dien-2-yl) benzo[d]thiazol derivatives", 
  "url": "https://aperta.ulakbim.gov.tr/record/55717"
}
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