1 Ocak 2017 Dergi makalesi Açık Erişim

Olah, Zoltan; Redei, Dora; Pecze, Laszlo; Vizler, Csaba; Josvay, Katalin; Forgo, Peter; Winter, Zoltan; Dombi, Gyorgy; Szakonyi, Gerda; Hohmann, Judit

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    <subfield code="a">Background: Transient Receptor Potential Vanilloid 1 (TRPV1) confers noxious heat and inflammatory pain signals in the peripheral nervous system. Clinical trial of resiniferatoxin from Euphorbia species is successfully aimed at TRPV1 in cancer pain management and heading toward new selective painkiller status that further validates this target for drug discovery efforts. Evodia species, used in traditional medicine for hundreds of years, are a recognised source of different TRPV1 agonists, but no antagonist has yet been reported.</subfield>
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