1 Ocak 2017 Dergi makalesi Açık Erişim

Oz, Pinar; Yertutanol, F. Duygu Kaya; Gozler, Tayfun; Ozcetin, Aye; Uzbay, I. Tayfun

DataCite XML

<?xml version='1.0' encoding='utf-8'?>
<resource xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://datacite.org/schema/kernel-4" xsi:schemaLocation="http://datacite.org/schema/kernel-4 http://schema.datacite.org/meta/kernel-4.1/metadata.xsd">
  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/48945</identifier>
  <creators>
    <creator>
      <creatorName>Oz, Pinar</creatorName>
      <givenName>Pinar</givenName>
      <familyName>Oz</familyName>
    </creator>
    <creator>
      <creatorName>Yertutanol, F. Duygu Kaya</creatorName>
      <givenName>F. Duygu Kaya</givenName>
      <familyName>Yertutanol</familyName>
    </creator>
    <creator>
      <creatorName>Gozler, Tayfun</creatorName>
      <givenName>Tayfun</givenName>
      <familyName>Gozler</familyName>
      <affiliation>Uskudar Univ, NPARC, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Ozcetin, Aye</creatorName>
      <givenName>Aye</givenName>
      <familyName>Ozcetin</familyName>
      <affiliation>Uskudar Univ, NPARC, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Uzbay, I. Tayfun</creatorName>
      <givenName>I. Tayfun</givenName>
      <familyName>Uzbay</familyName>
    </creator>
  </creators>
  <titles>
    <title>Lesions Of The Paraventricular Thalamic Nucleus Attenuates Prepulse Inhibition Of The Acoustic Startle Reflex</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2017</publicationYear>
  <dates>
    <date dateType="Issued">2017-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/48945</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1016/j.neulet.2017.01.056</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">The paraventricular thalamic nucleus (PVT) is a midline nucleus with strong connections to cortical and subcortical brain regions such as the prefrontal cortex, amygdala, nucleus accumbens and hippocampus and receives strong projections from brain stem nuclei. Prepulse inhibition (PPI) is mediated and modulated by complex cortical and subcortical networks that are yet to be fully identified in detail. Here, we suggest that the PVT may be an important brain region for the modulation of PPI. In our study, the paraventricular thalamic nuclei of rats were electrolytically lesioned. Two weeks after the surgery, the PPI responses of the animals were monitored and recorded using measurements of acoustic startle reflex. Our results show that disruption of the PVT dramatically attenuated PPI at prepulse intensities of 74,78 and 86 dB compared to that in the sham lesion group. Thus, we suggest that the PVT may be an important part of the PPI network in the rat brain. (C) 2017 Elsevier B.V. All rights reserved.</description>
  </descriptions>
</resource>