1 Ocak 2017 Dergi makalesi Açık Erişim

Demir, Gokce; Gurdere, Meliha Burcu; Ceylan, Mustafa; Budak, Yakup

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/46819</identifier>
  <creators>
    <creator>
      <creatorName>Demir, Gokce</creatorName>
      <givenName>Gokce</givenName>
      <familyName>Demir</familyName>
      <affiliation>Gaziosmanpasa Univ, Fac Arts &amp; Sci, Dept Chem, TR-60250 Tokat, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Gurdere, Meliha Burcu</creatorName>
      <givenName>Meliha Burcu</givenName>
      <familyName>Gurdere</familyName>
      <affiliation>Gaziosmanpasa Univ, Fac Arts &amp; Sci, Dept Chem, TR-60250 Tokat, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Ceylan, Mustafa</creatorName>
      <givenName>Mustafa</givenName>
      <familyName>Ceylan</familyName>
      <affiliation>Gaziosmanpasa Univ, Fac Arts &amp; Sci, Dept Chem, TR-60250 Tokat, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Budak, Yakup</creatorName>
      <givenName>Yakup</givenName>
      <familyName>Budak</familyName>
      <affiliation>Gaziosmanpasa Univ, Fac Arts &amp; Sci, Dept Chem, TR-60250 Tokat, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Synthesis And Anti-Bacterial Activity Of Novel 1,3-Phenylene-Bis-N-Acetyl- And N-Phenylpyrazole Derivatives</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2017</publicationYear>
  <dates>
    <date dateType="Issued">2017-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/46819</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.25135/acg.oc.12.16.12.453</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">The 1,1'-(5,5'-(1,3-phenylene) bis(3-aryl-4,5-dihydro-1H-pyrazole-5,1-diyl)) di-ethanone (5a-e) and 1,3-bis(1-phenyl-3-(aryl)-4,5-dihydro-1H-pyrazol-5-yl) benzene (6a-e) were synthesized by addition of hydrazine hydrate and/or phenylhydrazine to 1,3-phenylene-bis-chalcone derivatives (3a-e), respectively. The structures of obtained compounds (5a-e and 6a-e) were characterized using the spectroscopic methods (NMR, IR) and elemental analysis. Addition, the in vitro antibacterial activities of compounds (5a-e) was tested against the five human pathogenic bacteria. Gentamycin and Fluconazole were used as positive control. The results were given as inhibition zone (mm) and the compounds 5d and 5e showed the same activity with standard (Fluconazole) against C. albinas.</description>
  </descriptions>
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