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Activatable Photosensitizers: Agents for Selective Photodynamic Therapy

Li, Xingshu; Kolemen, Safacan; Yoon, Juyoung; Akkaya, Engin U.


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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/45769</identifier>
  <creators>
    <creator>
      <creatorName>Li, Xingshu</creatorName>
      <givenName>Xingshu</givenName>
      <familyName>Li</familyName>
      <affiliation>Ewha Womans Univ, Dept Chem &amp; Nano Sci, Seoul 120750, South Korea</affiliation>
    </creator>
    <creator>
      <creatorName>Kolemen, Safacan</creatorName>
      <givenName>Safacan</givenName>
      <familyName>Kolemen</familyName>
      <affiliation>Bilkent Univ, UNAM Inst Mat Sci &amp; Nanotechnol, TR-06800 Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Yoon, Juyoung</creatorName>
      <givenName>Juyoung</givenName>
      <familyName>Yoon</familyName>
      <affiliation>Ewha Womans Univ, Dept Chem &amp; Nano Sci, Seoul 120750, South Korea</affiliation>
    </creator>
    <creator>
      <creatorName>Akkaya, Engin U.</creatorName>
      <givenName>Engin U.</givenName>
      <familyName>Akkaya</familyName>
    </creator>
  </creators>
  <titles>
    <title>Activatable Photosensitizers: Agents For Selective Photodynamic Therapy</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2017</publicationYear>
  <dates>
    <date dateType="Issued">2017-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/45769</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1002/adfm.201604053</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Recent developments in the design of bifunctional and activatable photo-sensitizers rejuvenate the aging field of photodynamic sensitization and photodynamic therapy. While systematic studies have uncovered new dyes that can serve as potential photosensitizers, the most promising results have come from studies aimed at gaining precise control over the location and rate of cytotoxic singlet oxygen generation. As a consequence, higher selectivities and efficiencies in photodynamic treatment protocols are now within reach. This feature article highlights the variety of approaches that have been pursued to improve photodynamic therapy and to transform simple photosensitizers into smarter theranostic agents.</description>
  </descriptions>
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