1 Ocak 2017 Dergi makalesi Açık Erişim

Kavakli, Ibrahim Halil; Baris, Ibrahim; Tardu, Mehmet; Gul, Seref; Oner, Hasimcan; Cal, Sibel; Bulut, Selma; Yarparvar, Darya; Berkel, Caglar; Ustaoglu, Pinar; Aydin, Cihan

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/44207</identifier>
  <creators>
    <creator>
      <creatorName>Kavakli, Ibrahim Halil</creatorName>
      <givenName>Ibrahim Halil</givenName>
      <familyName>Kavakli</familyName>
    </creator>
    <creator>
      <creatorName>Baris, Ibrahim</creatorName>
      <givenName>Ibrahim</givenName>
      <familyName>Baris</familyName>
      <affiliation>Koc Univ, Dept Mol Biol &amp; Genet, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Tardu, Mehmet</creatorName>
      <givenName>Mehmet</givenName>
      <familyName>Tardu</familyName>
      <affiliation>Koc Univ, Dept Computat Sci &amp; Engn, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Gul, Seref</creatorName>
      <givenName>Seref</givenName>
      <familyName>Gul</familyName>
      <affiliation>Koc Univ, Dept Chem &amp; Biol Engn, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Oner, Hasimcan</creatorName>
      <givenName>Hasimcan</givenName>
      <familyName>Oner</familyName>
      <affiliation>Koc Univ, Dept Chem &amp; Biol Engn, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Cal, Sibel</creatorName>
      <givenName>Sibel</givenName>
      <familyName>Cal</familyName>
      <affiliation>Koc Univ, Dept Mol Biol &amp; Genet, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Bulut, Selma</creatorName>
      <givenName>Selma</givenName>
      <familyName>Bulut</familyName>
      <affiliation>Koc Univ, Dept Chem &amp; Biol Engn, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Yarparvar, Darya</creatorName>
      <givenName>Darya</givenName>
      <familyName>Yarparvar</familyName>
      <affiliation>Koc Univ, Dept Chem &amp; Biol Engn, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Berkel, Caglar</creatorName>
      <givenName>Caglar</givenName>
      <familyName>Berkel</familyName>
      <affiliation>Koc Univ, Dept Mol Biol &amp; Genet, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Ustaoglu, Pinar</creatorName>
      <givenName>Pinar</givenName>
      <familyName>Ustaoglu</familyName>
      <affiliation>Koc Univ, Dept Mol Biol &amp; Genet, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Aydin, Cihan</creatorName>
      <givenName>Cihan</givenName>
      <familyName>Aydin</familyName>
      <affiliation>Istanbul Medeniyet Univ, Dept Mol Biol &amp; Genet, Istanbul, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>The Photolyase/Cryptochrome Family Of Proteins As Dna Repair Enzymes And Transcriptional Repressors</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2017</publicationYear>
  <dates>
    <date dateType="Issued">2017-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/44207</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1111/php.12669</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Light is a very important environmental factor that governs many cellular responses in organisms. As a consequence, organisms possess different kinds of light-sensing photoreceptors to regulate their physiological variables and adapt to a given habitat. The cryptochrome/photolyase family (CPF) includes photoreceptors that perform different functions in different organisms. Photolyases repair ultraviolet-induced DNA damage by a process known as photoreactivation using photons absorbed from the blue end of the light spectrum. On the other hand, cryptochromes act as blue light circadian photoreceptors in plants and Drosophila to regulate growth and development. In mammals, cryptochromes have light-independent functions and are very important transcriptional regulators that act at the molecular level as negative transcriptional regulators of the circadian clock. In this review, we highlight current knowledge concerning the structural and functional relationships of CPF members.</description>
  </descriptions>
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