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Immunoproteomic analysis of Bordetella pertussis and identification of new immunogenic proteins

Altindis, Emrah; Tefon, Burcu E.; Yildirim, Volkan; Ozcengiz, Erkan; Becher, Doete; Hecker, Michael; Ozcengiz, Gulay


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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/41773</identifier>
  <creators>
    <creator>
      <creatorName>Altindis, Emrah</creatorName>
      <givenName>Emrah</givenName>
      <familyName>Altindis</familyName>
      <affiliation>Middle E Tech Univ, Dept Biol Sci, TR-06531 Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Tefon, Burcu E.</creatorName>
      <givenName>Burcu E.</givenName>
      <familyName>Tefon</familyName>
      <affiliation>Middle E Tech Univ, Dept Biol Sci, TR-06531 Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Yildirim, Volkan</creatorName>
      <givenName>Volkan</givenName>
      <familyName>Yildirim</familyName>
      <affiliation>Middle E Tech Univ, Dept Biol Sci, TR-06531 Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Ozcengiz, Erkan</creatorName>
      <givenName>Erkan</givenName>
      <familyName>Ozcengiz</familyName>
      <affiliation>Vaccine Biol Res Co, Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Becher, Doete</creatorName>
      <givenName>Doete</givenName>
      <familyName>Becher</familyName>
      <affiliation>Ernst Moritz Arndt Univ Greifswald, Inst Mikrobiol, D-17487 Greifswald, Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Hecker, Michael</creatorName>
      <givenName>Michael</givenName>
      <familyName>Hecker</familyName>
      <affiliation>Ernst Moritz Arndt Univ Greifswald, Inst Mikrobiol, D-17487 Greifswald, Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Ozcengiz, Gulay</creatorName>
      <givenName>Gulay</givenName>
      <familyName>Ozcengiz</familyName>
      <affiliation>Middle E Tech Univ, Dept Biol Sci, TR-06531 Ankara, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Immunoproteomic Analysis Of Bordetella Pertussis And Identification Of New Immunogenic Proteins</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2009</publicationYear>
  <dates>
    <date dateType="Issued">2009-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/41773</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1016/j.vaccine.2008.11.020</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Bordetella pertussis is the causative agent of highly communicable respiratory infection whooping cough (pertussis) which remains one of the world's leading causes of vaccine-preventable deaths. In the present study, total soluble proteins extracted from two B. pertussis strains, Tohama I and the local isolate Saadet were separated by two-dimensional gel electrophoresis and analyzed by Western blotting for their reactivity with the antisera obtained from the mice immunized with inactivated whole cells as well as those collected from the mice challenged intraperitoneally with live cells of each strain. Of a total of 25 immunogenic proteins identified, 21 were shown to be the novel antigens for B. pertussis. (C) 2008 Elsevier Ltd. All rights reserved.</description>
  </descriptions>
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