1 Ocak 2020 Dergi makalesi Açık Erişim

Adiguzel, Mehmet Cemal; Baran, Alper; Wu, Zuowei; Cengiz, Seyda; Dai, Lei; Oz, Cihan; Ozmenli, Esma; Goulart, Debora Brito; Sahin, Orhan

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{
  "@context": "https://schema.org/", 
  "@id": 4109, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "name": "Adiguzel, Mehmet Cemal"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ataturk Univ, Erzurum Vocat Sch, Dept Food Qual Control & Anal, Erzurum, Turkey", 
      "name": "Baran, Alper"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Iowa State Univ, Coll Vet Med, Dept Vet Microbiol & Prevent Med, Ames, IA 50011 USA", 
      "name": "Wu, Zuowei"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ataturk Univ, Fac Vet Med, Dept Microbiol, Erzurum, Turkey", 
      "name": "Cengiz, Seyda"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Iowa State Univ, Coll Vet Med, Dept Vet Microbiol & Prevent Med, Ames, IA 50011 USA", 
      "name": "Dai, Lei"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ataturk Univ, Fac Vet Med, Dept Microbiol, Erzurum, Turkey", 
      "name": "Oz, Cihan"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ataturk Univ, Fac Vet Med, Dept Microbiol, Erzurum, Turkey", 
      "name": "Ozmenli, Esma"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Iowa State Univ, Coll Vet Med, Dept Vet Microbiol & Prevent Med, Ames, IA 50011 USA", 
      "name": "Goulart, Debora Brito"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Iowa State Univ, Coll Vet Med, Dept Vet Diagnost & Prod Anim Med, Ames, IA 50011 USA", 
      "name": "Sahin, Orhan"
    }
  ], 
  "datePublished": "2020-01-01", 
  "description": "Colistin is one of the most effective antibiotics against multidrug resistant Gram-negative bacteria. However, the recent emergence of plasmid-borne mobilized colistin resistance (mcr) genes is considered a serious antimicrobial resistance challenge worldwide. In this study, we report detection of anmcr-1carryingEscherichia coliisolate (named ATAVETmcr-1 Turkey) from retail raw chicken meat in Turkey. Of the 11 (from 500 total tested) phenotypically colistin-resistant isolates, 1 was shown to carry themcr-1gene by PCR. Whole-genome sequencing indicated thatmcr-1was located on a similar to 13 kb-long contig that was almost identical to the corresponding part in pZJ1635, an IncI2 plasmid encodingmcr-1in the same genetic context in anotherE. colistrain. In addition, ATAVETmcr-1 Turkey harboredbla(CTX-M-8),qnrB19,mdf(A),tet(A),sul2,aph(3 '')-Ib,aph(6)-Id, andfloRresistance genes. Phylogenetic analysis based on whole genome and multilocus sequence typing indicated that ATAVETmcr-1 Turkey was more closely related tomcr-1carryingE. coliisolates from food and human clinical samples previously reported from different parts of the world than to those from Turkey. These findings further emphasize the worldwide emergence and spread ofmcrmeditated colistin resistance in bacteria with zoonotic potential within animals and the food chain.", 
  "headline": "Prevalence of Colistin Resistance inEscherichia coliin Eastern Turkey and Genomic Characterization of anmcr-1Positive Strain from Retail Chicken Meat", 
  "identifier": 4109, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Prevalence of Colistin Resistance inEscherichia coliin Eastern Turkey and Genomic Characterization of anmcr-1Positive Strain from Retail Chicken Meat", 
  "url": "https://aperta.ulakbim.gov.tr/record/4109"
}