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Decreased expression of beta(1)- and beta(2)-adrenoceptors in human diabetic atrial appendage

Dincer, U. Deniz; Guner, Sahika; Tay, Aydin; Arioglu, Ebru; Tasdelen, Atilay; Aslamaci, Sait; Bidasee, Keshore R.


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        "affiliation": "Ankara Univ, Fac Pharm, Dept Pharmacol, TR-06100 Ankara, Turkey", 
        "name": "Dincer, U. Deniz"
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      {
        "affiliation": "Ankara Univ, Fac Pharm, Dept Pharmacol, TR-06100 Ankara, Turkey", 
        "name": "Guner, Sahika"
      }, 
      {
        "affiliation": "Ankara Univ, Fac Pharm, Dept Pharmacol, TR-06100 Ankara, Turkey", 
        "name": "Tay, Aydin"
      }, 
      {
        "affiliation": "Ankara Univ, Fac Pharm, Dept Pharmacol, TR-06100 Ankara, Turkey", 
        "name": "Arioglu, Ebru"
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      {
        "affiliation": "Baskent Univ, Sch Med, Dept Cardiovasc Surg, TR-06490 Ankara, Turkey", 
        "name": "Tasdelen, Atilay"
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      {
        "affiliation": "Baskent Univ, Sch Med, Dept Cardiovasc Surg, TR-06490 Ankara, Turkey", 
        "name": "Aslamaci, Sait"
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      {
        "affiliation": "Univ Nebraska Med Ctr, Dept Pharmacol, Omaha, NE USA", 
        "name": "Bidasee, Keshore R."
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    "description": "Background: Using the streptozotocin-induced diabetic rat model, we have recently showed that the expression and function of beta(1)-adrenoreceptor were decreased in the diabetic rat heart. However, the effect of diabetes on expression of beta-adrenoreceptors in human cardiac tissue remains undefined. Therefore, the focus of the present study was to investigate the effect of diabetes on mRNA encoding beta(1)- and beta(2)-ARs in human atrial tissues.", 
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      "title": "CARDIOVASCULAR DIABETOLOGY", 
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