1 Ocak 2009 Dergi makalesi Açık Erişim

Akkiprik, Mustafa; Hu, Limei; Sahin, Aysegul; Hao, Xishan; Zhang, Wei

DataCite XML

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/39459</identifier>
  <creators>
    <creator>
      <creatorName>Akkiprik, Mustafa</creatorName>
      <givenName>Mustafa</givenName>
      <familyName>Akkiprik</familyName>
    </creator>
    <creator>
      <creatorName>Hu, Limei</creatorName>
      <givenName>Limei</givenName>
      <familyName>Hu</familyName>
      <affiliation>Univ Texas MD Anderson Canc Ctr, Dept Pathol, Houston, TX 77030 USA</affiliation>
    </creator>
    <creator>
      <creatorName>Sahin, Aysegul</creatorName>
      <givenName>Aysegul</givenName>
      <familyName>Sahin</familyName>
      <affiliation>Univ Texas MD Anderson Canc Ctr, Dept Pathol, Houston, TX 77030 USA</affiliation>
    </creator>
    <creator>
      <creatorName>Hao, Xishan</creatorName>
      <givenName>Xishan</givenName>
      <familyName>Hao</familyName>
      <affiliation>Tianjin Med Univ, Tianjin Canc Inst &amp; Hosp, Tianjin, Peoples R China</affiliation>
    </creator>
    <creator>
      <creatorName>Zhang, Wei</creatorName>
      <givenName>Wei</givenName>
      <familyName>Zhang</familyName>
      <affiliation>Univ Texas MD Anderson Canc Ctr, Dept Pathol, Houston, TX 77030 USA</affiliation>
    </creator>
  </creators>
  <titles>
    <title>The Subcellular Localization Of Igfbp5 Affects Its Cell Growth And Migration Functions In Breast Cancer</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2009</publicationYear>
  <dates>
    <date dateType="Issued">2009-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/39459</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1186/1471-2407-9-103</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Background: Insulin-like growth factor binding protein 5 (IGFBP5) has been shown to be associated with breast cancer metastasis in clinical marker studies. However, a major difficulty in understanding how IGFBP5 functions in this capacity is the paradoxical observation that ectopic overexpression of IGFBP5 in breast cancer cell lines results in suppressed cellular proliferation. In cancer tissues, IGFBP5 resides mainly in the cytoplasm; however, in transfected cells, IGFBP5 is mainly located in the nucleus. We hypothesized that subcellular localization of IGFBP5 affects its functions in host cells.</description>
  </descriptions>
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