1 Ocak 2020 Dergi makalesi Açık Erişim

Elmas, Gamze; Okumus, Aytug; Kilic, Zeynel; Ozbeden, Pelin; Acik, Leyla; Tunali, Beste Cagdas; Turk, Mustafa; Cerci, Nebahat Aytuna; Hokelek, Tuncer

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/3625</identifier>
  <creators>
    <creator>
      <creatorName>Elmas, Gamze</creatorName>
      <givenName>Gamze</givenName>
      <familyName>Elmas</familyName>
      <affiliation>Ankara Univ, Dept Chem, TR-06100 Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Okumus, Aytug</creatorName>
      <givenName>Aytug</givenName>
      <familyName>Okumus</familyName>
      <affiliation>Ankara Univ, Dept Chem, TR-06100 Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Kilic, Zeynel</creatorName>
      <givenName>Zeynel</givenName>
      <familyName>Kilic</familyName>
      <affiliation>Ankara Univ, Dept Chem, TR-06100 Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Ozbeden, Pelin</creatorName>
      <givenName>Pelin</givenName>
      <familyName>Ozbeden</familyName>
      <affiliation>Gazi Univ, Dept Biol, TR-06500 Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Acik, Leyla</creatorName>
      <givenName>Leyla</givenName>
      <familyName>Acik</familyName>
      <affiliation>Gazi Univ, Dept Biol, TR-06500 Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Tunali, Beste Cagdas</creatorName>
      <givenName>Beste Cagdas</givenName>
      <familyName>Tunali</familyName>
      <affiliation>Kirikkale Univ, Dept Bioengn, TR-71450 Kirikkale, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Turk, Mustafa</creatorName>
      <givenName>Mustafa</givenName>
      <familyName>Turk</familyName>
      <affiliation>Kirikkale Univ, Dept Bioengn, TR-71450 Kirikkale, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Cerci, Nebahat Aytuna</creatorName>
      <givenName>Nebahat Aytuna</givenName>
      <familyName>Cerci</familyName>
      <affiliation>Gazi Univ, Dept Biol, TR-06500 Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Hokelek, Tuncer</creatorName>
      <givenName>Tuncer</givenName>
      <familyName>Hokelek</familyName>
      <affiliation>Hacettepe Univ, Dept Phys, TR-06800 Ankara, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Phosphorus-Nitrogen Compounds. Part 48. Syntheses Of The Phosphazenium Salts Containing 2-Pyridyl Pendant Arm: Structural Characterizations, Thermal Analysis, Antimicrobial And Cytotoxic Activity Studies</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2020</publicationYear>
  <dates>
    <date dateType="Issued">2020-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/3625</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsVersionOf">10.81043/aperta.3624</relatedIdentifier>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.81043/aperta.3625</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">The phosphazenium salts (protic ionic liquids, PILs/protic molten salts, PMOSs) (6a-6d and 7a) of the free phosphazene bases (4a-4d and 5a) have been prepared by the reactions of the corresponding cyclotriphosphazenes with the bulky gentisic acid. The structures of the PMOS have been evaluated using the elemental analyses, FTIR, H-1, C-13{H-1} and P-31{H-1} NmR data. The molecular and crystal structures of 4a and 6c are established by X-ray crystallography. The thermal properties of the PMOS are determined using TG and DTA techniques. On the other hand, the antimicrobial activities of the free phosphazene bases (4a-4d and 5a-5d) and PMOSs (6a-6d and 7a) are screened against the selected bacteria and yeast strains. The antimicrobial activities of the free phosphazene bases and the PMOSs are compared. The interactions of the phosphazenes and their salts with plasmid DNA are elucidated by the agarose gel electrophoresis. The evaluations of the cytotoxic activities of these compounds are also studied against to L929 fibroblast and breast cancer cells (MDA-MB-231).</description>
  </descriptions>
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