1 Ocak 2020 Dergi makalesi Açık Erişim

Goktas, Zeynep; Zu, Yujiao; Abbasi, Mehrnaz; Galyean, Shannon; Wu, Dayong; Fan, Zhaoyang; Wang, Shu

MARC21 XML

<?xml version='1.0' encoding='UTF-8'?>
<record xmlns="http://www.loc.gov/MARC21/slim">
  <leader>00000nam##2200000uu#4500</leader>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="a">Zu, Yujiao</subfield>
    <subfield code="u">Texas Tech Univ, Dept Nutr Sci, Lubbock, TX 79409 USA</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="a">Abbasi, Mehrnaz</subfield>
    <subfield code="u">Texas Tech Univ, Dept Nutr Sci, Lubbock, TX 79409 USA</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="a">Galyean, Shannon</subfield>
    <subfield code="u">Texas Tech Univ, Dept Nutr Sci, Lubbock, TX 79409 USA</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="a">Wu, Dayong</subfield>
    <subfield code="u">Tufts Univ, Nutr Immunol Lab, Jean Mayer USDA Human Nutr Res Ctr Aging, Boston, MA 02111 USA</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="a">Fan, Zhaoyang</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="a">Wang, Shu</subfield>
    <subfield code="u">Texas Tech Univ, Dept Nutr Sci, Lubbock, TX 79409 USA</subfield>
  </datafield>
  <datafield tag="909" ind1="C" ind2="4">
    <subfield code="p">JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY</subfield>
    <subfield code="v">68</subfield>
    <subfield code="n">31</subfield>
    <subfield code="c">8119-8131</subfield>
  </datafield>
  <datafield tag="980" ind1=" " ind2=" ">
    <subfield code="a">user-tubitak-destekli-proje-yayinlari</subfield>
  </datafield>
  <datafield tag="540" ind1=" " ind2=" ">
    <subfield code="a">Creative Commons Attribution</subfield>
    <subfield code="u">http://www.opendefinition.org/licenses/cc-by</subfield>
  </datafield>
  <datafield tag="024" ind1=" " ind2=" ">
    <subfield code="a">10.1021/acs.jafc.0c00131</subfield>
    <subfield code="2">doi</subfield>
  </datafield>
  <datafield tag="245" ind1=" " ind2=" ">
    <subfield code="a">Recent Advances in Nanoencapsulation of Phytochemicals to Combat Obesity and Its Comorbidities</subfield>
  </datafield>
  <datafield tag="100" ind1=" " ind2=" ">
    <subfield code="a">Goktas, Zeynep</subfield>
    <subfield code="u">Hacettepe Univ, Fac Hlth Sci, Dept Nutr &amp; Dietet, TR-06100 Ankara, Turkey</subfield>
  </datafield>
  <datafield tag="909" ind1="C" ind2="O">
    <subfield code="o">oai:zenodo.org:3449</subfield>
    <subfield code="p">user-tubitak-destekli-proje-yayinlari</subfield>
  </datafield>
  <datafield tag="650" ind1="1" ind2="7">
    <subfield code="2">opendefinition.org</subfield>
    <subfield code="a">cc-by</subfield>
  </datafield>
  <datafield tag="260" ind1=" " ind2=" ">
    <subfield code="c">2020-01-01</subfield>
  </datafield>
  <datafield tag="856" ind1="4" ind2=" ">
    <subfield code="u">https://aperta.ulakbim.gov.trrecord/3449/files/bib-fcea77f2-c906-450f-ab31-fd240fd3bc97.txt</subfield>
    <subfield code="z">md5:a8bcbcf467c663caa54947ba4988beaa</subfield>
    <subfield code="s">238</subfield>
  </datafield>
  <datafield tag="542" ind1=" " ind2=" ">
    <subfield code="l">open</subfield>
  </datafield>
  <controlfield tag="005">20210315054603.0</controlfield>
  <controlfield tag="001">3449</controlfield>
  <datafield tag="980" ind1=" " ind2=" ">
    <subfield code="a">publication</subfield>
    <subfield code="b">article</subfield>
  </datafield>
  <datafield tag="520" ind1=" " ind2=" ">
    <subfield code="a">An increasing epidemic of obesity has become a serious public health concern primarily because it contributes to pathogenesis of many chronic diseases including type 2 diabetes, cardiovascular disease, hepatobiliary disease, obstructive sleep apnea, kidney disease, some types of cancer, among others. Consumption of a variety of phytochemicals has emerged as a promising potential for combating obesity and its comorbidities. However, the generally low aqueous solubility, stability, bioavailability, and target specificity of phytochemicals, along with their side-effects and toxicity seen when used at high doses, have restricted their clinical applications. As a solution, phytochemicals can be encapsulated into nanoparticles to increase their stability and solubility, enhance their bioavailability, protect them from premature degradation in the body, prolong their circulation time, and thus enhance their antiobesity activity. In this perspective, we summarize the problems and limitations of the prominent phytochemicals (epigallocatechin gallate, trans-resveratrol, curcumin, and quercetin), the major biocompatible and biodegradable nanoparticles, and the efficacy of nanoencapsulated forms of these phytochemicals in combating obesity and its comorbidities.</subfield>
  </datafield>
</record>