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Cakmak, Osman; Okten, Salih; Alimli, Dilek; Saddiqa, Aisha; Ersanli, Cem Cuneyt
{
"DOI": "10.24820/ark.5550190.p010.374",
"abstract": "Quinoline forms the key skeletal component of a number of important natural products and pharmacologically-active compounds. Despite a tremendous amount of research pertaining to the derivatization of quinoline, very few general synthetic routes are described in the literature starting from quinoline or tetrahydroquinoline. A simple and convenient method for the polyfunctionalization of quinolines via nitration of bromoquinolines has been developed. This method represents a new synthetic approach to convert brominated nitroquinoline derivatives into useful cyclic amines via nucleophilic-substitution (SNAr) reaction.",
"author": [
{
"family": "Cakmak",
"given": " Osman"
},
{
"family": "Okten",
"given": " Salih"
},
{
"family": "Alimli",
"given": " Dilek"
},
{
"family": "Saddiqa",
"given": " Aisha"
},
{
"family": "Ersanli",
"given": " Cem Cuneyt"
}
],
"container_title": "ARKIVOC",
"id": "33959",
"issued": {
"date-parts": [
[
2018,
1,
1
]
]
},
"page": "362-374",
"title": "Activation of 6-bromoquinoline by nitration: synthesis of morpholinyl and piperazinyl quinolines",
"type": "article-journal"
}
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