1 Ocak 2018 Dergi makalesi Açık Erişim

Maden, M.; Yildiz, R.; Col, R.; Arican, M.; Ider, M.; Garip, M.; Tras, B.

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    <subfield code="a">The evaluation of hemostatic dysfunction and disseminated intravascular coagulation in dairy cows with abomasal displacement</subfield>
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    <subfield code="p">POLISH JOURNAL OF VETERINARY SCIENCES</subfield>
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    <subfield code="a">Disseminated intravascular coagulation (DIC) is a complex, dynamic and hemostatic disorder which develops secondarily to a disease characterized with an imbalance in the pro-coagulant and anti-coagulant components of hemostasis. The aim of the study is to evaluate hemostatic dysfunction and the DIC syndrome in cattle with displaced abomasum (DA), with using the hematologic analyses and an extensive coagulation profile in the 96 hour-period including before and after surgery. The animal material of the study consisted of 12 dairy cows diagnosed with displaced abomasum (9 LDA and 3 RDA without volvulus) in the 2-4 week period after parturation and with no other post-partum disease. In dairy cows diagnosed with DA, hematological, coagulometric (PT, APTT, Fibrinogen) and coagulation factor analyses [D-Dimer, TAT (thrombin-antithrombin complex), ATIII (antithrombin III), PAI-1 (plazminogen activator inhibitor-1] were performed in blood samples obtained before the operation as well as 30 minutes, 60 minutes and 2, 5, 10, 24, 48, 72 and 96 hours after the operation. In the DA cases, abnormalities were found in 6 of the 8 coagulation parameters. In the LDA and RDA groups, prolonged PT (sec), PT (INR) and APTT, hypofibrinogenemia, an increase in serum D-Dimer concentration at 72 and 96 hours after the operation and an increase in serum ATIII concentrations before and 30, 60 minutes and 2, 5, 72 and 96 hours after the operation was found (p&amp;lt;0.05). Hemostatic dysfunction and the risk of DIC developing in DA cases and continuing in the post-operative period was determined.</subfield>
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    <subfield code="u">Mehmet Akif Univ, Dept Internal Med, Fac Vet Med, TR-15030 Burdur, Turkey</subfield>
    <subfield code="a">Yildiz, R.</subfield>
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    <subfield code="u">Selcuk Univ, Dept Physiol, Fac Vet Med, TR-42003 Konya, Turkey</subfield>
    <subfield code="a">Col, R.</subfield>
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    <subfield code="u">Selcuk Univ, Dept Surg, Fac Vet Med, TR-42003 Konya, Turkey</subfield>
    <subfield code="a">Arican, M.</subfield>
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    <subfield code="a">Ider, M.</subfield>
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    <subfield code="u">Selcuk Univ, Dept Anim Breeding, Fac Vet Med, TR-42003 Konya, Turkey</subfield>
    <subfield code="a">Garip, M.</subfield>
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    <subfield code="u">Selcuk Univ, Dept Pharmacol &amp; Toxicol, Fac Vet Med, TR-42003 Konya, Turkey</subfield>
    <subfield code="a">Tras, B.</subfield>
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    <subfield code="u">Selcuk Univ, Dept Internal Med, Fac Vet Med, TR-42003 Konya, Turkey</subfield>
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    <subfield code="a">10.24425/pjvs.2018.125590</subfield>
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