1 Ocak 2018 Dergi makalesi Açık Erişim

Ozek, Gulmira; Bedir, Erdal; Tabanca, Nurhayat; Ali, Abbas; Khan, Ikhlas A.; Duran, Ahmet; Baser, Kemal H. C.; Ozek, Temel

Dublin Core

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  <dc:creator>Ozek, Gulmira</dc:creator>
  <dc:creator>Bedir, Erdal</dc:creator>
  <dc:creator>Tabanca, Nurhayat</dc:creator>
  <dc:creator>Ali, Abbas</dc:creator>
  <dc:creator>Khan, Ikhlas A.</dc:creator>
  <dc:creator>Duran, Ahmet</dc:creator>
  <dc:creator>Baser, Kemal H. C.</dc:creator>
  <dc:creator>Ozek, Temel</dc:creator>
  <dc:date>2018-01-01</dc:date>
  <dc:description>In the present work, an endemic species Prangos heyniae collected in four locations from Turkey was subjected to hydrodistillation in Clevenger type apparatus to obtain the essential oils (E01-4). The gas chromatography/mass spectrometry (GC/MS) and gas chromatography-flame ionization detector (GC/FID) analyses showed that the EOs were rich in sesquiterpenes, germacrene D (10.3-12.1%), beta-bisabolene (14.4%), kessane (26.9%), germacrene B (8.2%), elemol (3.4-46.9%), beta-bisabolenal (14-70.7%), beta-bisabolenol (8.4%) and an eudesmane type sesquiterpene (1) (16.1%) with [M(+)218]. This unidentified compound (1) was isolated in a rapid one-step manner with &gt;95.0% purity using Preparative Capillary Gas Chromatography (PCGC) with an HP Innowax column connected to a Preparative Fraction Collector (PFC) system. Structure determination was accomplished from 1D- and 2D-NMR spectroscopic data which determined a new eudesmane type sesquiterpene, 3,7(11)-eudesmadien-2-one (1). Using a biting deterrent bioassay, the mean proportion not biting (PNB) values of the P. heyniae E01-4 were 0.88 for E01 and 0.80 for E02 which were similar to the positive control DEET (N, N-diethyl-3-methylbenzamide). The E03 and E04 had lower PNB values of 0.64 and 0.44, respectively. P. heyniae E01-4 showed good larvicidal activity at 125 and 62.5 ppm whereas E01-3 were slightly less effective at the dose of 31.25 ppm and E04 was not active at 31.25 ppm against 1st instar Aedes aegypti.</dc:description>
  <dc:identifier>https://aperta.ulakbim.gov.trrecord/31247</dc:identifier>
  <dc:identifier>oai:zenodo.org:31247</dc:identifier>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>http://www.opendefinition.org/licenses/cc-by</dc:rights>
  <dc:source>OPEN CHEMISTRY 16(1) 453-467</dc:source>
  <dc:title>Isolation of eudesmane type sesquiterpene ketone from Prangos heyniae H.Duman &amp; MFWatson essential oil and mosquitocidal activity of the essential oils</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
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