1 Ocak 2018 Dergi makalesi Açık Erişim

Kaya, Muhammet

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{
  "@context": "https://schema.org/", 
  "@id": 28937, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Eskisehir Osmangazi Univ, Dept Agr Biotechnol, Fac Agr, TR-26160 Eskisehir, Turkey", 
      "name": "Kaya, Muhammet"
    }
  ], 
  "datePublished": "2018-01-01", 
  "description": "Avian leukosis viruses (ALV) are retroviruses that can induce tumors in chicken. Typically, ALV is controlled through husbandry. However, genetic improvement and/or, selective breeding techniques, offer the unique possibility of true resistance. The tumor virus B (TVB) locus transcribes the cellular receptor that mediates an infection through B, D, and E subgroups of avian leukosis virus. Two single nucleotide polymorphisms (SNPs) at nucleotide positions 172 and 184 of the TVB locus account for the three major alleles, TVB*S1, TVB*S3, and TVB*R. The receptor encoded by TVB*R allele prevents viral entry into the cell of ALVB, ALVD, or ALVE subgroups. In this study, both SNPs at the TVB locus of Turkish native chicken breeds were investigated using a PCR-RFLP technique to detect. In both Gerze and Denizli breeds, the TVB*S1 allele was common and TVB*S3 was rare, respectively. The TVB*R allele was rare in the Gerze population and absent in the Denizli population. Allele frequencies of TVB*S1, TVB*S3, and TVB*R were evaluated as 0.96, 0.02, and 0.02 in Gerze chickens and 0.98, 0.02, and 0.00, in Denizli chickens, respectively.", 
  "headline": "Determination of the Tumor Virus B Locus in Turkish Native Chicken Breeds", 
  "identifier": 28937, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Determination of the Tumor Virus B Locus in Turkish Native Chicken Breeds", 
  "url": "https://aperta.ulakbim.gov.tr/record/28937"
}