1 Ocak 2010 Dergi makalesi Açık Erişim

Bayrak, Hacer; Demirbas, Ahmet; Bektas, Hakan; Karaoglu, Sengul Alpay; Demirbas, Neslihan

JSON

{
  "conceptrecid": "28212", 
  "created": "2021-03-15T12:32:17.470812+00:00", 
  "doi": "10.3906/kim-1004-570", 
  "files": [
    {
      "bucket": "045c1f2d-6574-488a-ae3b-969e33bbdccc", 
      "checksum": "md5:eb3d80d8022c1b2b1597f117f9551c4b", 
      "key": "10-3906-kim-1004-570.pdf", 
      "links": {
        "self": "https://aperta.ulakbim.gov.tr/api/files/045c1f2d-6574-488a-ae3b-969e33bbdccc/10-3906-kim-1004-570.pdf"
      }, 
      "size": 269255, 
      "type": "pdf"
    }
  ], 
  "id": 28213, 
  "links": {
    "badge": "https://aperta.ulakbim.gov.tr/badge/doi/10.3906/kim-1004-570.svg", 
    "bucket": "https://aperta.ulakbim.gov.tr/api/files/045c1f2d-6574-488a-ae3b-969e33bbdccc", 
    "doi": "https://doi.org/10.3906/kim-1004-570", 
    "html": "https://aperta.ulakbim.gov.tr/record/28213", 
    "latest": "https://aperta.ulakbim.gov.tr/api/records/28213", 
    "latest_html": "https://aperta.ulakbim.gov.tr/record/28213"
  }, 
  "metadata": {
    "access_right": "open", 
    "access_right_category": "success", 
    "communities": [
      {
        "id": "tubitak-destekli-proje-yayinlari"
      }
    ], 
    "creators": [
      {
        "affiliation": "Karadeniz Tech Univ, Dept Chem, Fac Arts & Sci, TR-61080 Trabzon, Turkey", 
        "name": "Bayrak, Hacer"
      }, 
      {
        "affiliation": "Karadeniz Tech Univ, Dept Chem, Fac Arts & Sci, TR-61080 Trabzon, Turkey", 
        "name": "Demirbas, Ahmet"
      }, 
      {
        "affiliation": "Giresun Univ, Fac Sci, Dept Chem, TR-28100 Giresun, Turkey", 
        "name": "Bektas, Hakan"
      }, 
      {
        "affiliation": "Rize Univ, Dept Biol, TR-53100 Rize, Turkey", 
        "name": "Karaoglu, Sengul Alpay"
      }, 
      {
        "affiliation": "Karadeniz Tech Univ, Dept Chem, Fac Arts & Sci, TR-61080 Trabzon, Turkey", 
        "name": "Demirbas, Neslihan"
      }
    ], 
    "description": "The synthesis of ethyl [3-(cyanomethyl)-5-alkyl-4H-1,2,4-triazol-4-yl] carbamates (2a-d) was performed starting from ethyl 2-[ethoxy(4-(aryl) methylene] hydrazinecarboxylates (1a, 1b). The treatment of 2a with thiosemicarbazide afforded ethyl [3-[(5-amino-1,3,4-thiadiazol-2-yl) methyl]-5-(4-nitrophenyl)-4H-1,2,4-triazol- 4-yl] carbamates (3a), whereas compound 2b produced 5-{[4-amino-5-(4-methylphenyl)-4H -1,2,4-triazol-3-yl] methyl}-1,3,4-thiadiazol-2-amine (3b) in the same reaction conditions. The treatment of tert butyl 2-[2-(4-chlorophenyl)-1-ethoxyethylidene] hydrazinecarboxylate (5) with malonohydrazide or cyanoacethydrazide gave the corresponding 1,2,4-triazol-ylcarbamate derivatives (6 or 9); then the hydrolysis of these compounds resulted in the formation of 3-{[4-amino-5-(4-chlorobenzyl)-4H -1,2,4-triazol-3-yl] methyl}5-(4-chlorobenzyl)-4H -1,2,4-triazol-4-amine (7) and [4-amino-5-(4-chlorobenzyl)-4H -1,2,4-triazole-3-yl] acetonitrile (10), respectively. The synthesis of the Schiff base derivatives 3-(4-chlorobenzyl)-5-{[5-(4-chlorobenzyl)-4-[(2-hydroxyphenyl-methylene) amino]-4H -1,2,4-triazol-3-yl] methyl}-N-(2-hydroxyphenylmethylene)4H-1,2,4-triazol-4-amine (8), and (5-(4-chlorobenzyl)-4-{[(2,6-dichlorophenyl) methylene] amino}-4H -1,2,4-triazol-3-yl) acetonitrile (12) was performed from the reaction of compounds 7 and 10 with salicyl aldehyde (for 8) or 2,6-dichlorobenzaldehyde (for 12), respectively. The treatment of compounds 5 or 10 with thiosemicarbazide gave 5-{[4-amino-5-(4-chlorobenzyl)-4H -1,2,4-triazol-3-yl] methyl}-1,3,4-thiadiazol-2-amine (11).", 
    "doi": "10.3906/kim-1004-570", 
    "has_grant": false, 
    "journal": {
      "issue": "6", 
      "pages": "835-846", 
      "title": "TURKISH JOURNAL OF CHEMISTRY", 
      "volume": "34"
    }, 
    "license": {
      "id": "cc-by"
    }, 
    "publication_date": "2010-01-01", 
    "relations": {
      "version": [
        {
          "count": 1, 
          "index": 0, 
          "is_last": true, 
          "last_child": {
            "pid_type": "recid", 
            "pid_value": "28213"
          }, 
          "parent": {
            "pid_type": "recid", 
            "pid_value": "28212"
          }
        }
      ]
    }, 
    "resource_type": {
      "subtype": "article", 
      "title": "Dergi makalesi", 
      "type": "publication"
    }, 
    "title": "Synthesis and antimicrobial activities of some new 1,2,4-triazole derivatives"
  }, 
  "owners": [
    1
  ], 
  "revision": 1, 
  "stats": {
    "downloads": 48.0, 
    "unique_downloads": 47.0, 
    "unique_views": 85.0, 
    "version_downloads": 48.0, 
    "version_unique_downloads": 47.0, 
    "version_unique_views": 82.0, 
    "version_views": 85.0, 
    "version_volume": 12924240.0, 
    "views": 90.0, 
    "volume": 12924240.0
  }, 
  "updated": "2021-03-15T12:32:17.512174+00:00"
}