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The Middle East and North Africa Diagnosis and Management Guidelines for Inborn Errors of Immunity

Baris, Safa; Abolhassani, Hassan; Massaad, Michel J.; Al-Nesf, Maryam; Chavoshzadeh, Zahra; Keles, Sevgi; Reisli, Ismail; Tahiat, Azzeddine; Shendi, Hiba Mohammad; Abd Elaziz, Dalia; Belaid, Brahim; Al Dhaheri, Fatima; Haskologlu, Sule; Dogu, Figen; Ben-Mustapha, Imen; Sobh, Ali; Galal, Nermeen; Meshaal, Safa; Elhawary, Rabab; El-marsafy, Aisha


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        "name": "Baris, Safa"
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      {
        "name": "Abolhassani, Hassan"
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      {
        "name": "Massaad, Michel J."
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      {
        "affiliation": "Hamad Med Corp, Allergy & Immunol Div, Dept Med, Doha, Qatar", 
        "name": "Al-Nesf, Maryam"
      }, 
      {
        "affiliation": "Shahid Beheshti Univ Med Sci, Mofid Children Hosp, Allergy & Clin Immunol Dept, Tehran, Iran", 
        "name": "Chavoshzadeh, Zahra"
      }, 
      {
        "affiliation": "Nec mettin Erbakan Univ, Meram Fac Med, Div Pediat Allergy & Immunol, Konya, MA USA", 
        "name": "Keles, Sevgi"
      }, 
      {
        "affiliation": "Nec mettin Erbakan Univ, Meram Fac Med, Div Pediat Allergy & Immunol, Konya, MA USA", 
        "name": "Reisli, Ismail"
      }, 
      {
        "affiliation": "Univ Algiers, Rouiba Hosp, Dept Med Biol, Lab Immunol, Fevzi Cakmak Mah 41, TR-34668 Algiers, Algeria", 
        "name": "Tahiat, Azzeddine"
      }, 
      {
        "affiliation": "Tawam Hosp, Div Pediat Allergy & Immunol, Abu Dhabi, U Arab Emirates", 
        "name": "Shendi, Hiba Mohammad"
      }, 
      {
        "affiliation": "Cairo Univ, Fac Med, Dept Pediat, Cairo, Egypt", 
        "name": "Abd Elaziz, Dalia"
      }, 
      {
        "affiliation": "Beni Messous Univ Hosp Ctr, Univ Algiers, Fac Pharm, Dept Med Immunol, Algiers, Algeria", 
        "name": "Belaid, Brahim"
      }, 
      {
        "affiliation": "United Arab Emirates Univ, Coll Med & Hlth Sci, Dept Pediat Pediat Infect Dis, Al Ain, U Arab Emirates", 
        "name": "Al Dhaheri, Fatima"
      }, 
      {
        "affiliation": "Ankara Univ, Dept Pediat Immunol & Allergy, Sch Med, Ankara, Turkiye", 
        "name": "Haskologlu, Sule"
      }, 
      {
        "affiliation": "Ankara Univ, Dept Pediat Immunol & Allergy, Sch Med, Ankara, Turkiye", 
        "name": "Dogu, Figen"
      }, 
      {
        "affiliation": "Univ Tunis El Manar, Inst Pasteur Tunis, Dept Immunol, Tunis, Tunisia", 
        "name": "Ben-Mustapha, Imen"
      }, 
      {
        "affiliation": "Mansoura Univ, Mansoura Univ Childrens Hosp, Fac Med, Dept Pediat, Mansoura, Egypt", 
        "name": "Sobh, Ali"
      }, 
      {
        "affiliation": "Cairo Univ, Fac Med, Dept Pediat, Cairo, Egypt", 
        "name": "Galal, Nermeen"
      }, 
      {
        "affiliation": "Cairo Univ, Fac Med, Clin Pathol Dept, Cairo, Egypt", 
        "name": "Meshaal, Safa"
      }, 
      {
        "affiliation": "Cairo Univ, Fac Med, Clin Pathol Dept, Cairo, Egypt", 
        "name": "Elhawary, Rabab"
      }, 
      {
        "affiliation": "Cairo Univ, Fac Med, Dept Pediat, Cairo, Egypt", 
        "name": "El-marsafy, Aisha"
      }
    ], 
    "description": "<p>Human inborn errors of immunity (IEI) are a group of 485 distinct genetic disorders affecting children and adults. Signs and symptoms of IEI are heterogeneous, and accurate diagnosis can be challenging and depends on the available human expertise and laboratory resources. The Middle East and North Africa (MENA) region has an increased prevalence of IEI because of the high rate of consanguinity with a predominance of autosomal recessive disorders. This area also exhibits more severe disease phenotypes compared with other regions, probably due to the delay in diagnosis. The MENA-IEI registry network has designed protocols and guidelines for the diagnosis and treatment of IEI, taking into consideration the variable regional expertise and resources. These guidelines are primarily meant to improve the care of patients within the region, but can also be followed in other regions with similar patient pop-ulations. (c) 2022 American Academy of Allergy, Asthma &amp; Immunology</p>", 
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    "title": "The Middle East and North Africa Diagnosis and Management Guidelines for Inborn Errors of Immunity"
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