Dergi makalesi Açık Erişim

Preliminary Report of the Academic CAR-T (ISIKOK-19) Cell Clinical Trial in Turkey: Characterization of Product and Outcomes of Clinical Application

2022    Erdogan, Ebru; Yalcin, Koray; Hemsinlioglu, Cansu; Sezgin, Aslihan; Seyis, Utku; Kancagi, Derya Dilek; Tastan, Cihan; Yurtsever, Bulut; Turan, Raife Dilek; Cakirsoy, Didem; Abanuz, Selen; Karakus, Gozde Sir; Elek, Muhammer; Bekoz, Huseyin Saffet; Gemici, Ali Ihsan; Sargin, Deniz; Arat, Mutlu; Ferhanoglu, Burhan; Pekguc, Ebru; Ornek, Serdar; Ornek, Serdar

Objective: Chimeric antigen receptor T (CAR-T) cell therapies have already made an impact on the treatment of B-cell malignancies. Although CAR-T cell therapies are promising, there are concerns about commercial products regarding their affordability and sustainability. In this preliminary study, the results of the first production and clinical data of an academic CAR-T cell (ISIKOK-19) trial in Turkey are presented.