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Characterization and investigation of properties of copper nanoparticle coated TiO2 nanotube surfaces on Ti6Al4V alloy

Durdu, Salih; Tosun, Sergen; Yalcin, Emine; Cavusoglu, Kultigin; Altinkok, Atilgan; Sagcan, Hasan; Yurtsever, Ilknur; Usta, Metin


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        "name": "Durdu, Salih"
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      {
        "affiliation": "Giresun Univ, Dept Mech Engn, TR-28200 Giresun, Turkey", 
        "name": "Tosun, Sergen"
      }, 
      {
        "affiliation": "Giresun Univ, Dept Biol, TR-28200 Giresun, Turkey", 
        "name": "Yalcin, Emine"
      }, 
      {
        "affiliation": "Giresun Univ, Dept Biol, TR-28200 Giresun, Turkey", 
        "name": "Cavusoglu, Kultigin"
      }, 
      {
        "affiliation": "Natl Def Univ, Turkish Naval Acad, TR-34940 Istanbul, Turkey", 
        "name": "Altinkok, Atilgan"
      }, 
      {
        "affiliation": "Istanbul Medipol Univ, Dept Med Lab Tech, Istanbul, Turkey", 
        "name": "Sagcan, Hasan"
      }, 
      {
        "affiliation": "Istanbul Medipol Univ, Dept Med Lab Tech, Istanbul, Turkey", 
        "name": "Yurtsever, Ilknur"
      }, 
      {
        "affiliation": "Gebze Tech Univ, Dept Mat Sci & Engn, TR-41400 Gebze, Turkey", 
        "name": "Usta, Metin"
      }
    ], 
    "description": "In this work, to investigate surface, corrosion and in vitro biological properties of the CuNPs-coated nanotube surfaces, antibacterial, bioactive and biocompatible nanoparticle-coated nanotube surfaces were produced on Ti6Al4V alloys by combined anodic oxidation (AO) and electrodeposition (ED) techniques for implant applications. All surfaces were characterized by SEM, EDX-mapping and -area, XRD, AFM and contact angle measurement techniques. The electrochemical and biological properties such as antibacterial activities, protein adsorption, ALP activity, hemolytic activity and cell viability of the surfaces were investigated in detail. Electrochemical corrosion resistance of CuNPs-coated nanotube surfaces were enhanced respect to uncoated Ti6Al4V alloy under simulated body fluid (SBF) conditions. Antibacterial properties, cell viability and ALP activity of CuNPs-coated nanotube surfaces were improved with compared to uncoated Ti6Al4V alloys. In addition, protein adsorption and hemolytic activity of CuNPs-coated nanotube surfaces were reduced. This work indicates a potential to precisely fabricate an antibacterial, bioactive and biocompatible CuNPs-coated nanotube surfaces on Ti6Al4V to fulfill orthopedic and dental implant needs by using combined AO and ED processes.", 
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      "title": "MATERIALS CHEMISTRY AND PHYSICS", 
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    "title": "Characterization and investigation of properties of copper nanoparticle coated TiO2 nanotube surfaces on Ti6Al4V alloy"
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