1 Ocak 2022 Dergi makalesi Açık Erişim

Agus, Sami; Akkaya, Hatice; Daglioglu, Nebile; Eyuboglu, Signem; Atasayan, Ozge; Mete, Fatih; Colak, Cemil; Sandal, Suleyman; Yilmaz, Bayram

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    "creators": [
      {
        "affiliation": "Yeditepe Univ, Fac Med, Dept Physiol, TR-34755 Istanbul, Turkey", 
        "name": "Agus, Sami"
      }, 
      {
        "affiliation": "Univ Hlth Sci, Fac Pharm, Dept Biochem, Istanbul, Turkey", 
        "name": "Akkaya, Hatice"
      }, 
      {
        "affiliation": "Culcurova Univ, Fac Med, Dept Forens Med, Adana, Turkey", 
        "name": "Daglioglu, Nebile"
      }, 
      {
        "affiliation": "Yeditepe Univ, Fac Med, Dept Physiol, TR-34755 Istanbul, Turkey", 
        "name": "Eyuboglu, Signem"
      }, 
      {
        "affiliation": "Yeditepe Univ, Fac Med, Dept Physiol, TR-34755 Istanbul, Turkey", 
        "name": "Atasayan, Ozge"
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      {
        "affiliation": "Kanuni Sultan Suleyman Training & Res Hosp, Dept Pediat, Istanbul, Turkey", 
        "name": "Mete, Fatih"
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      {
        "affiliation": "Inonu Univ, Fac Med, Dept Physiol, Malatya, Turkey", 
        "name": "Colak, Cemil"
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      {
        "affiliation": "Inonu Univ, Fac Med, Dept Physiol, Malatya, Turkey", 
        "name": "Sandal, Suleyman"
      }, 
      {
        "affiliation": "Yeditepe Univ, Fac Med, Dept Physiol, TR-34755 Istanbul, Turkey", 
        "name": "Yilmaz, Bayram"
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    "description": "Persistent organic pollutants (POPs) continue to threaten the environment and human health. We have investigated levels of polychlorinated biphenyls (PCBs) and organochlorinated pesticides (OCPs) in breast milk samples. A questionnaire was also obtained from the study participants. A total of 48 healthy lactating mothers (mean age: 29.5 +/- 0.8 years) living in Istanbul volunteered to participate in this study. High-resolution analyses of several OCPs and PCB congeners were done by gas chromatography. The levels of seven major PCB congeners (28, 52, 101, 118, 138, 153, and 180) and eight OCPs (alpha-benzenehexachloride, beta-benzenehexachloride, delta-benzenehexachloride, hexachlorobenzene (HCB), and 2,4 '-dichlorodiphenyldichloroethylene (2,4DDE), 4,4 '-dichlorodiphenyldichloroethylene (4,4DDE), 2,4 '-dichlorodiphenyltrichloroethane (2,4DDT), and 4,4 '-dichlorodiphenyltrichloroethane (4,4DDT)) were determined. The analysis showed that the highest levels of PCBs were observed in PCB 52 (22.99 +/- 8.78 ng/g lipid), PCB 101 (12.22 +/- 7.8 ng/g lipid), PCB 28 (11.44 +/- 5.16 ng/g lipid), and PCB 153 (1.70 +/- 0.74 ng/g lipid). The highest OCPs detected were 4,4DDT (3.33 +/- 2.05 ng/g lipid) and 4,4DDE (0.86 +/- 0.39 ng/g lipid), and the lowest was observed in HCB (0.016 +/- 0.01 ng/g lipid). Our findings show that traces of PCBs and OCPs are still present in breast milk of lactating women living in Istanbul, and these pollutants decline in multipara women compared to primipara mothers. We also suggest that breast milk is a useful and representative biological tool for human biomonitoring of POPs.", 
    "doi": "10.1007/s11356-021-15863-6", 
    "has_grant": false, 
    "journal": {
      "issue": "3", 
      "pages": "3463-3473", 
      "title": "ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH", 
      "volume": "29"
    }, 
    "license": {
      "id": "cc-by"
    }, 
    "publication_date": "2022-01-01", 
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      "title": "Dergi makalesi", 
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    "title": "Polychlorinated biphenyls and organochlorine pesticides in breast milk samples and their correlation with dietary and reproductive factors in lactating mothers in Istanbul"
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