Konferans bildirisi Açık Erişim
Sengul, Ibrahim F.; Bingul, Murat; Kandemir, Hakan; Kumar, Naresh; Black, David StC.
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<identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/236722</identifier>
<creators>
<creator>
<creatorName>Sengul, Ibrahim F.</creatorName>
<givenName>Ibrahim F.</givenName>
<familyName>Sengul</familyName>
<affiliation>Gebze Tech Univ, Dept Chem, Fac Sci, Kocaeli, Turkey</affiliation>
</creator>
<creator>
<creatorName>Bingul, Murat</creatorName>
<givenName>Murat</givenName>
<familyName>Bingul</familyName>
<affiliation>Dicle Univ, Dept Pharmaceut Chem, Fac Pharm, TR-21280 Diyarbakir, Turkey</affiliation>
</creator>
<creator>
<creatorName>Kandemir, Hakan</creatorName>
<givenName>Hakan</givenName>
<familyName>Kandemir</familyName>
<affiliation>Tekirdag Namik Kemal Univ, Fac Art & Sci, Dept Chem, Tekirdag, Turkey</affiliation>
</creator>
<creator>
<creatorName>Kumar, Naresh</creatorName>
<givenName>Naresh</givenName>
<familyName>Kumar</familyName>
<affiliation>UNSW Sydney, Sch Chem, Sydney, NSW 2052, Australia</affiliation>
</creator>
<creator>
<creatorName>Black, David StC.</creatorName>
<givenName>David StC.</givenName>
<familyName>Black</familyName>
<affiliation>UNSW Sydney, Sch Chem, Sydney, NSW 2052, Australia</affiliation>
</creator>
</creators>
<titles>
<title>Synthesis, Reactivity And Biological Properties Of Methoxy-Activated Indoles</title>
</titles>
<publisher>Aperta</publisher>
<publicationYear>2021</publicationYear>
<dates>
<date dateType="Issued">2021-01-01</date>
</dates>
<resourceType resourceTypeGeneral="Text">Conference paper</resourceType>
<alternateIdentifiers>
<alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/236722</alternateIdentifier>
</alternateIdentifiers>
<relatedIdentifiers>
<relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.17374/targets.2022.25.162</relatedIdentifier>
</relatedIdentifiers>
<rightsList>
<rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
<rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
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<descriptions>
<description descriptionType="Abstract">Indoles continue to play a central role in the development of new structures of chemical and biological interest. They are the source of numerous biologically active natural products by virtue of their derivation from tryptophan units which are essential to peptide, protein and enzyme structures. Although the indole unit is electron rich and displays a wide range of reactivity, many naturally-occurring indoles contain methoxy substituents, which enhance their reactivity. The synthesis of methoxyindoles has also become a strategy for diversifying the regiochemical behaviour of indoles. This review brings together a wide range of information relating to indoles incorporating one, two, or three methoxy groups. It deals with aspects of synthesis, reactivity, and biological activity as well as summarizing the scope of important natural products.</description>
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