1 Ocak 2021 Dergi makalesi Açık Erişim

Bakirci, Sibel; Ayan, Gizem; Gazel, Ummugulsum; Tinazzi, Ilaria; Solmaz, Dilek; Kasapoglu, Esen; Kalyoncu, Umut; Aydin, Sibel Zehra

JSON-LD (schema.org)

{
  "@context": "https://schema.org/", 
  "@id": 233700, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "name": "Bakirci, Sibel"
    }, 
    {
      "@type": "Person", 
      "name": "Ayan, Gizem"
    }, 
    {
      "@type": "Person", 
      "name": "Gazel, Ummugulsum"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Sacro Cuore Don Calabria Hosp, Unit Rheumatol, Verona, VR, Italy", 
      "name": "Tinazzi, Ilaria"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Izmir Katip Celebi Univ, Dept Internal Med, Div Rheumatol, Izmir, Turkey", 
      "name": "Solmaz, Dilek"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Medeniyet Univ, Goztepe Res & Training Hosp, Istanbul, Turkey", 
      "name": "Kasapoglu, Esen"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Hacettepe Univ, Dept Internal Med, Div Rheumatol, Ankara, Turkey", 
      "name": "Kalyoncu, Umut"
    }, 
    {
      "@type": "Person", 
      "name": "Aydin, Sibel Zehra"
    }
  ], 
  "datePublished": "2021-01-01", 
  "description": "Psoriatic arthritis (PsA) is a heterogeneous disease with both environmental and genetic factors playing a role in this diversity. The aim of this study is to compare the patient profiles and outcomes in PsA patients in three countries from three continents. PsA patients from Turkey (n = 184), Canada (n = 200), and Italy (n = 177) from the Psoriatic Arthritis-International Database (PsArt-ID) were compared for patient demographics, disease features, treatments, and minimal disease activity (MDA) rates. Patient profiles were different across countries, patients from Italy being older [median (Q1-Q3): 59 (51-65)] than patients from Turkey [48 (37-58)] and Canada [55 (44-65)] and Italian patients having more frequent comorbidities and being more frequently smokers. For disease phenotypes, patients from Italy had axial disease less frequently (12%) than others (Turkey 23%, Canada 52%). Similarly, disease activity in patients from Italy was higher with higher tender and swollen joint counts and body surface area for psoriasis. The lowest rate of biologic use was observed in Italy [ Italy: 18.4%, Turkey: 26.1%, Canada: 33.9%]. MDA was achieved more in Canada [OR (CI): Canada vs Italy = 3.326 (1.983-5.577); Canada vs Turkey = 2.392 (1.498-3.818); Turkey vs Italy = 1.391 (0.786-2.460)]. PsA patient characteristics differ across countries which may be leading to differences in treatments and MDA rates. The differences can be a combination of genetic or geographical differences as well as the demographics of the general population in that area. Therefore, the unmet needs of PsA patients may vary globally.", 
  "headline": "Patient characteristics and minimal disease activity in psoriatic arthritis: a transcontinental comparison", 
  "identifier": 233700, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Patient characteristics and minimal disease activity in psoriatic arthritis: a transcontinental comparison", 
  "url": "https://aperta.ulakbim.gov.tr/record/233700"
}