1 Ocak 2021 Dergi makalesi Açık Erişim

Arslan, Mehmet; Sevgiler, Yusuf; Guven, Celal; Murathan, Zehra Tugba; Erbil, Nurcan; Yildirim, Deniz; Buyukleyla, Mehmet; Karadas, Sakire; Celik, Rima; Rencuzogullari, Eyyup

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/230840</identifier>
  <creators>
    <creator>
      <creatorName>Arslan, Mehmet</creatorName>
      <givenName>Mehmet</givenName>
      <familyName>Arslan</familyName>
      <affiliation>Ardahan Univ, Dept Hlth Management, Fac Hlth Sci, Ardahan, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Sevgiler, Yusuf</creatorName>
      <givenName>Yusuf</givenName>
      <familyName>Sevgiler</familyName>
      <affiliation>Adiymnan Univ, Dept Biol, Fac Sci &amp; Letters, TR-02040 Adiyaman, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Guven, Celal</creatorName>
      <givenName>Celal</givenName>
      <familyName>Guven</familyName>
      <affiliation>Nigde Omer Halisdemir Univ, Dept Biophys, Fac Med, Nigde, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Murathan, Zehra Tugba</creatorName>
      <givenName>Zehra Tugba</givenName>
      <familyName>Murathan</familyName>
      <affiliation>Malatya Turgut Ozal Univ, Battalgazi Vocat Sch, Battalgazi, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Erbil, Nurcan</creatorName>
      <givenName>Nurcan</givenName>
      <familyName>Erbil</familyName>
      <affiliation>Ardahan Univ, Dept Nursing, Fac Hlth Sci, Ardahan, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Yildirim, Deniz</creatorName>
      <givenName>Deniz</givenName>
      <familyName>Yildirim</familyName>
      <affiliation>Cukurova Univ, Dept Chem Engn, Fac Ceyhan Engn, Ceyhan, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Buyukleyla, Mehmet</creatorName>
      <givenName>Mehmet</givenName>
      <familyName>Buyukleyla</familyName>
      <affiliation>Ardahan Univ, Ardahan Vocat Sch Hlth Serv, Ardahan, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Karadas, Sakire</creatorName>
      <givenName>Sakire</givenName>
      <familyName>Karadas</familyName>
      <affiliation>Kahramanmaras Sutcu Imam Univ, Dept Biol, Fac Sci &amp; Letters, Kahramanmaras, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Celik, Rima</creatorName>
      <givenName>Rima</givenName>
      <familyName>Celik</familyName>
      <affiliation>Kilis 7 Aralik Univ, Dept Mol Biol &amp; Genet, Fac Sci &amp; Letters, Kilis, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Rencuzogullari, Eyyup</creatorName>
      <givenName>Eyyup</givenName>
      <familyName>Rencuzogullari</familyName>
      <affiliation>Adiymnan Univ, Dept Biol, Fac Sci &amp; Letters, TR-02040 Adiyaman, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Chemical And Biological Characteristics Of Propolis From Apis Mellifera Caucasica From The Ardahan And Erzurum Provinces Of Turkey: A Comparative Study</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2021</publicationYear>
  <dates>
    <date dateType="Issued">2021-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/230840</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.2478/aiht-2021-72-3492</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">The aim of this study was to compare the biological activities of ethanolic propolis extracts of Apis mellifera caucasica obtained from Ardahan and Erzurum provinces of Turkey. Samples were tested for antioxidant, anticytotoxic, anticarcinogenic, antibacterial, and antifungal potentials using different techniques. Propolis samples from the two provinces had different mineral and organic compositions related to their geographical origin. The ferric reducing antioxidant power (FRAP) test showed superiority of Ardahan propolis over the Erzurum. Regardless of origin and the presence of mitomycin C in the culture medium, propolis enhanced human peripheral lymphocyte viability, which depended on the duration and propolis concentration. Antiperoxidative activity on MCF-7 breast cancer cells was concentration-dependent. Erzurum propolis showed the highest anticarcinogenic activity at the concentrations of 62.5 mu g/mL and 125 mu g/mL, which dropped at higher concentrations. All propolis samples also showed antibacterial activity against the tested human pathogens similar to ampicillin and penicillin controls, except for Pseudomonas aeruginosa. However, they did not exert any antifungal activity against Candida albicans and Yarrowia lipolytica. In conclusion, propolis samples from both provinces showed promising biological activities, but further research should focus on finding the right concentrations for optimal effect and include the cell necrosis pathway to get a better idea of the anticarcinogenic effects.</description>
  </descriptions>
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