1 Ocak 2021 Dergi makalesi Açık Erişim

Yaris, Esra; Adsiz, Leyla Balur; Yener, Ismail; Tuncay, Eyyup; Yilmaz, Mustafa Abdullah; Akdeniz, Mehmet; Kaplaner, Erhan; Firat, Mehmet; Ertas, Abdulselam; Kolak, Ufuk

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/229824</identifier>
  <creators>
    <creator>
      <creatorName>Yaris, Esra</creatorName>
      <givenName>Esra</givenName>
      <familyName>Yaris</familyName>
      <affiliation>Dicle Univ, Fac Pharm, Dept Pharmacognosy, TR-21280 Diyarbakir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Adsiz, Leyla Balur</creatorName>
      <givenName>Leyla Balur</givenName>
      <familyName>Adsiz</familyName>
      <affiliation>Dicle Univ, Fac Pharm, Dept Pharmacognosy, TR-21280 Diyarbakir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Yener, Ismail</creatorName>
      <givenName>Ismail</givenName>
      <familyName>Yener</familyName>
      <affiliation>Dicle Univ, Fac Pharm, Dept Analyt Chem, TR-21280 Diyarbakir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Tuncay, Eyyup</creatorName>
      <givenName>Eyyup</givenName>
      <familyName>Tuncay</familyName>
      <affiliation>Dicle Univ, Fac Pharm, Dept Pharmacognosy, TR-21280 Diyarbakir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Yilmaz, Mustafa Abdullah</creatorName>
      <givenName>Mustafa Abdullah</givenName>
      <familyName>Yilmaz</familyName>
      <affiliation>Dicle Univ, Sci &amp; Technol Res &amp; Applicat Ctr DUBTAM, TR-21280 Diyarbakir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Akdeniz, Mehmet</creatorName>
      <givenName>Mehmet</givenName>
      <familyName>Akdeniz</familyName>
      <affiliation>Council Forens Diyarbakir Grp Chairmanship, TR-21100 Diyarbakir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Kaplaner, Erhan</creatorName>
      <givenName>Erhan</givenName>
      <familyName>Kaplaner</familyName>
      <affiliation>Mugla Sitki Kocman Univ, Fac Sci, Dept Chem, TR-48121 Mugla, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Firat, Mehmet</creatorName>
      <givenName>Mehmet</givenName>
      <familyName>Firat</familyName>
      <affiliation>Van Yuzuncu Yil Univ, Fac Educ, Dept Biol, TR-65080 Van, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Ertas, Abdulselam</creatorName>
      <givenName>Abdulselam</givenName>
      <familyName>Ertas</familyName>
      <affiliation>Dicle Univ, Fac Pharm, Dept Pharmacognosy, TR-21280 Diyarbakir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Kolak, Ufuk</creatorName>
      <givenName>Ufuk</givenName>
      <familyName>Kolak</familyName>
      <affiliation>Istanbul Univ, Fac Pharm, Dept Gen &amp; Analyt Chem, TR-34116 Istanbul, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Isolation Of Secondary Metabolites Of Two Endemic Species: Salvia Rosifolia Sm. And Salvia Cerino-Pruinosa Rech. F. Var. Elazigensis (Lamiaceae)</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2021</publicationYear>
  <dates>
    <date dateType="Issued">2021-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/229824</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1007/s11694-021-01065-8</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">In the present study, activity-guided isolation and structural elucidation of antioxidant secondary metabolites of ethanol extracts prepared from the root and aerial parts of Salvia rosifolia and Salvia cerino-pruinosa var. elazigensis species was aimed. The ethanol extracts of the species were fractionated and the antioxidant capacities of the fractions were determined by DPPH-free radical and ABTS-cation radical scavenging activity, and cupric-reducing antioxidant capacity (CUPRAC) assays. Isolation studies of the fractions with high antioxidant activities were carried out. Thirty nine secondary metabolites of known structure were isolated from the active extracts. 17 of the isolated compounds are in phenolic-flavonoid structure, 4 of them are in fatty acid structure, 7 of them are in abietane type diterpene structure, 2 of which are paraquinone and 5 of which are in aromatic structure, 8 of them are in triterpene structure, 2 of which are ursane, 2 of which are oleane and 4 of which are lupane structure, and 3 of them are in steroid structure. The structures of the isolated compounds were determined by UV, IR, H-1- and C-13-NMR-(APT), HMQC-HMBC, LCMS-IT/TOF and GC-MS techniques. It was determined that phenolic compounds among the isolated compounds were more active than terpenoid compounds in all three methods.</description>
  </descriptions>
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