1 Ocak 2011 Dergi makalesi Açık Erişim

Zora, Metin; Kivrak, Arif; Yazici, Ceyda

Citation Style Language JSON

{
  "DOI": "10.1021/jo201119e", 
  "abstract": "Electrophilic cyclizations of alpha,beta-alkynic hydrazones by molecular iodine were investigated for the synthesis of 4-iodopyrazoles. alpha,beta-Alkynic hydrazones were readily prepared by the reactions of hydrazines with propargyl aldehydes and ketones. When treated with molecular iodine in the presence of sodium bicarbonate, alpha,beta-alkynic hydrazones underwent electrophilic cyclization to afford 4-iodopyrazoles in good to high yields. Iodocyclization was general for a wide range of alpha,beta-alkynic hydrazones and tolerated the presence of aliphatic, aromatic, heteroaromatic, and ferrocenyl moieties with electron-withdrawing and electron-donating substituents.", 
  "author": [
    {
      "family": "Zora", 
      "given": " Metin"
    }, 
    {
      "family": "Kivrak", 
      "given": " Arif"
    }, 
    {
      "family": "Yazici", 
      "given": " Ceyda"
    }
  ], 
  "container_title": "JOURNAL OF ORGANIC CHEMISTRY", 
  "id": "22263", 
  "issue": "16", 
  "issued": {
    "date-parts": [
      [
        2011, 
        1, 
        1
      ]
    ]
  }, 
  "page": "6726-6742", 
  "title": "Synthesis of Pyrazoles via Electrophilic Cyclization", 
  "type": "article-journal", 
  "volume": "76"
}