1 Ocak 2011 Dergi makalesi Açık Erişim

Bar, Amir; Kabakcioglu, Alkan; Mukamel, David

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    <subfield code="a">The denaturation transition which takes place in circular DNA is analyzed by extending the Poland-Scheraga (PS) model to include the winding degrees of freedom. We consider the case of a homopolymer whereby the winding number of the double-stranded helix, released by a loop denaturation, is absorbed by supercoils. We find that as in the case of linear DNA, the order of the transition is determined by the loop exponent c. However the first-order transition displayed by the PS model for c &amp;gt; 2 in linear DNA is replaced by a continuous transition with arbitrarily high order as c approaches 2, while the second-order transition found in the linear case in the regime 1 &amp;lt; c &amp;lt;= 2 disappears. In addition, our analysis reveals that melting under fixed linking number is a condensation transition, where the condensate is a macroscopic loop which appears above the critical temperature.</subfield>
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    <subfield code="a">10.1103/PhysRevE.84.041935</subfield>
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    <subfield code="a">Denaturation of circular DNA: Supercoil mechanism</subfield>
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    <subfield code="a">Mukamel, David</subfield>
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