1 Ocak 2013 Dergi makalesi Açık Erişim

Ada, Ahmet Oguz; Demiroglu, Canan; Yilmazer, Meltem; Suzen, Halit Sinan; Demirbag, Ali Eba; Efe, Sibel; Alemdar, Yilmaz; Iscan, Mumtaz; Burgaz, Sema

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/13265</identifier>
  <creators>
    <creator>
      <creatorName>Ada, Ahmet Oguz</creatorName>
      <givenName>Ahmet Oguz</givenName>
      <familyName>Ada</familyName>
      <affiliation>Ankara Univ, Fac Pharm, Dept Toxicol, Tandogan, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Demiroglu, Canan</creatorName>
      <givenName>Canan</givenName>
      <familyName>Demiroglu</familyName>
      <affiliation>Gazi Univ, Dept Toxicol, Fac Pharm, Etiler, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Yilmazer, Meltem</creatorName>
      <givenName>Meltem</givenName>
      <familyName>Yilmazer</familyName>
      <affiliation>Gazi Univ, Dept Toxicol, Fac Pharm, Etiler, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Suzen, Halit Sinan</creatorName>
      <givenName>Halit Sinan</givenName>
      <familyName>Suzen</familyName>
      <affiliation>Ankara Univ, Fac Pharm, Dept Toxicol, Tandogan, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Demirbag, Ali Eba</creatorName>
      <givenName>Ali Eba</givenName>
      <familyName>Demirbag</familyName>
      <affiliation>Yuksek Ihtisas Hosp, Gastrointestinal Surg Dept, Sihhiye, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Efe, Sibel</creatorName>
      <givenName>Sibel</givenName>
      <familyName>Efe</familyName>
      <affiliation>Eregli Iron &amp; Steel Works Co, Karadeniz Eregli, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Alemdar, Yilmaz</creatorName>
      <givenName>Yilmaz</givenName>
      <familyName>Alemdar</familyName>
      <affiliation>Eregli Iron &amp; Steel Works Co, Karadeniz Eregli, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Iscan, Mumtaz</creatorName>
      <givenName>Mumtaz</givenName>
      <familyName>Iscan</familyName>
      <affiliation>Ankara Univ, Fac Pharm, Dept Toxicol, Tandogan, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Burgaz, Sema</creatorName>
      <givenName>Sema</givenName>
      <familyName>Burgaz</familyName>
      <affiliation>Gazi Univ, Dept Toxicol, Fac Pharm, Etiler, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Cytogenetic Damage In Turkish Coke Oven Workers Expose L To Polycyclic Aromatic Hydrocarbons: Association With Cyp1A1, Cyp1B1, Ephx1, Gstm1, Gstt1, And Gstp1 Gene Polymorphisms</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2013</publicationYear>
  <dates>
    <date dateType="Issued">2013-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/13265</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.2478/10004-1254-64-2013-2328</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">The aim of this study was to determine the frequencies of chromosomal aberrations (CA) and cytochalasin-blocked micronuclei (CBMN) in peripheral blood lymphocytes from Turkish coke oven workers and the influence of CYP1A1, CYP1B1, EPHX1, GSTM1, GSTT1, and GSTP1 gene polymorphisms on these biomarkers. Cytogenetic analysis showed that occupational exposure significantly increased the CA and CBMN frequencies. Gene polymorphisms, on the other hand, did not affect CA or CBMN in either exposed or control subjects. However, due to the limited sample size, our findings need to be verified in future studies with a larger sample.</description>
  </descriptions>
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