1 Ocak 2013 Dergi makalesi Açık Erişim

Sariisik, Merih; Arici, Mesut; Topbas, Ozlem; Karavana, Sinem Yaprak; Ozturk, Cihat; Ertan, Gokhan

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/12523</identifier>
  <creators>
    <creator>
      <creatorName>Sariisik, Merih</creatorName>
      <givenName>Merih</givenName>
      <familyName>Sariisik</familyName>
      <affiliation>Dokuz Eylul Univ, Dept Text Engn, Izmir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Arici, Mesut</creatorName>
      <givenName>Mesut</givenName>
      <familyName>Arici</familyName>
      <affiliation>Ege Univ, Dept Pharmaceut Technol, Izmir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Topbas, Ozlem</creatorName>
      <givenName>Ozlem</givenName>
      <familyName>Topbas</familyName>
      <affiliation>Dokuz Eylul Univ, Dept Text Engn, Izmir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Karavana, Sinem Yaprak</creatorName>
      <givenName>Sinem Yaprak</givenName>
      <familyName>Karavana</familyName>
      <affiliation>Ege Univ, Dept Pharmaceut Technol, Izmir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Ozturk, Cihat</creatorName>
      <givenName>Cihat</givenName>
      <familyName>Ozturk</familyName>
      <affiliation>Ege Univ, Dept Phys Med &amp; Rehabil, Izmir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Ertan, Gokhan</creatorName>
      <givenName>Gokhan</givenName>
      <familyName>Ertan</familyName>
      <affiliation>Ege Univ, Dept Pharmaceut Technol, Izmir, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Design Of Orthopedic Support Material Containing Diclofenac Sodium Microparticles: Preparation And Characterization Of Microparticles And Application To Orthopedic Support Material</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2013</publicationYear>
  <dates>
    <date dateType="Issued">2013-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/12523</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1177/0040517512464292</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">The aim of this study is preparation and characterization of diclofenac sodium microparticles and their application to the orthopedic support materials. The microparticles were obtained using spray drying method involving ethyl cellulose as shell material. The morphology, particle size, drug loading capacity and in vitro release characteristics of the drug microparticles were optimized for impregnation diclofenac sodium microparticles onto the orthopedic support materials. Scanning electron microscopy (SEM) was used to characterize the drug microparticles and the treated fabrics with microparticles. SEM images illustrated that the microparticles were spherical in shape and also fixed onto the orthopedic support materials. Furthermore, the resistance of materials containing microparticles to washing were also investigated. Finally, in vitro drug release studies of microparticles and textile impregnated with microparticles were done. This study suggested that textile systems containing diclofenac sodium microparticles could have a potential for long-term therapy for rheumatic disorders.</description>
  </descriptions>
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