1 Ocak 2021 Dergi makalesi Açık Erişim

Aydingoz, Ikbal Esen; Demirci, Gulsen Tukenmez; Agirbasli, Deniz; Oz-Arslan, Devrim; Yenmis, Guven

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/10487</identifier>
  <creators>
    <creator>
      <creatorName>Aydingoz, Ikbal Esen</creatorName>
      <givenName>Ikbal Esen</givenName>
      <familyName>Aydingoz</familyName>
      <affiliation>Acibadem Mehmet Ali Aydinlar Univ, Sch Med, Dept Dermatol, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Demirci, Gulsen Tukenmez</creatorName>
      <givenName>Gulsen Tukenmez</givenName>
      <familyName>Demirci</familyName>
      <affiliation>Acibadem Mehmet Ali Aydinlar Univ, Sch Med, Dept Dermatol, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Agirbasli, Deniz</creatorName>
      <givenName>Deniz</givenName>
      <familyName>Agirbasli</familyName>
      <affiliation>Acibadem Mehmet Ali Aydinlar Univ, Sch Med, Dept Med Biol, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Oz-Arslan, Devrim</creatorName>
      <givenName>Devrim</givenName>
      <familyName>Oz-Arslan</familyName>
      <affiliation>Acibadem Mehmet Ali Aydinlar Univ, Sch Med, Dept Biophys, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Yenmis, Guven</creatorName>
      <givenName>Guven</givenName>
      <familyName>Yenmis</familyName>
      <affiliation>Biruni Univ, Sch Med, Dept Med Biol, Labgen Genet Diagnost Ctr,Acibadem Healthcare Ser, Istanbul, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>The Investigation Of The Amounts And Expressions Of Epidermal Growth Factor, Epidermal Growth Factor Receptor, And Epidermal Growth Factor Receptor Gene Polymorphisms In Acne Vulgaris</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2021</publicationYear>
  <dates>
    <date dateType="Issued">2021-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/10487</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1111/jocd.13498</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Background Epidermal growth factor receptor inhibitors (EGFRI) used in cancer chemotherapy cause acneiform folliculitis in 70%-100% of patients in a dose-dependent manner. Acneiform folliculitis is considered to be caused by an inflammatory process due to follicular hyperkeratosis and subsequently a set of changes both in epidermis and hair follicles as a result of epidermal growth factor receptor (EGFR) blockade. Both acne vulgaris and acneiform folliculitis due to EGFRIs show similar changes in the pilosebaceous unit. Furthermore, in both groups of patients, topical application of recombinant human epidermal growth factor (EGF) has been reported to improve the disease.</description>
  </descriptions>
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