Yayınlanmış 1 Ocak 2014 | Sürüm v1
Dergi makalesi Açık

Role of biomaterials in prevention of in-stent restenosis

  • 1. Mersin Univ, Res & Applicat Ctr, TR-33343 Mersin, Turkey
  • 2. TUBITAK MAM, Genet Engn & Biotechnol Inst, Enzyme & Fermentat Technol Lab, TR-41470 Gebze, Kocaeli, Turkey

Açıklama

Coronary balloon angioplasty and coronary stenting are the procedures used in healing coronary artery disease. However, injury of arteries during angioplasty and stenting causes cell stimulations in tissue. Cell movement and thrombosis lead to re-narrowing of widened vessel called restenosis. Several new types of carriers and technology have been developed to suppress and/or prevent restenosis. Authors review the polymeric materials featured in drug/gene carrier systems, nanovehicles, and stent coating materials against restenosis. (C) 2013 Wiley Periodicals, Inc.

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