Published January 1, 2017
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Antioxidant and Anticholinesterase Activities of Some Dialkylamino Substituted 3-Hydroxyflavone Derivatives
- 1. Istanbul Tech Univ, Fac Sci & Letters, Dept Chem, Istanbul, Turkey
- 2. Dicle Univ, Dept Pharmaceut Technol, Fac Pharm, Diyarbakir, Turkey
- 3. Mugla Sitki Kocman Univ, Dept Chem, Fac Sci, Mugla, Turkey
- 4. Bezmialem Vakif Univ, Dept Pharmacognosy Phytochem, Fac Pharm, Istanbul, Turkey
Description
Background: Flavones, are a class of naturally occuring polyphenolic compounds which have 2-phenylchromen-4-one structure. Various studies showed that flavones have several pharmacological activities such as antioxidant, anti-inflammatory, antimicrobial, cytotoxic, antitumour and antiallergic. In the present study, 3-hydroxyflavones also called flavonols, posessing 4'-dialkylamino moiety were synthesized, and their antioxidant and anticholinesterase activities were investigated by comparison with unmodified 3-hydroxflavone.
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