Published January 1, 2005
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DNA damaging activities of methanol extract of Ajuga postii and iridoid glucoside reptoside
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An iridoid glucoside reptoside ( 1) has been isolated as a DNA damaging active agent by bioassay-guided fractionation of the methanol extract of Ajuga postii. Furthermore, from the acetone extract of A. postii two known triterpenic compounds ursolic acid, alpha-amyrin and two steroidal compounds ( 24S)-24-ethylcholesta-5,25-dien-3 beta-ol and beta-sitosterol were isolated. Their structures were elucidated based on 1D and 2D NMR techniques and mass data.
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