Published January 1, 2020
| Version v1
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Localized Amyloid-like Accumulation in a Zebrafish (Danio rerio): A Case Report
Creators
- 1. Bingol Univ, Vocat Sch Hlth Serv, Dept Med Serv & Tech, TR-12000 Bingol, Turkey
- 2. Bingol Univ, Fac Vet, Med Dept Pathol, TR-12000 Bingol, Turkey
Description
Amyloidosis is described as collection of extracellular proteins with a characteristic fibrillar form with electron microscopy, a typical X-ray diffraction pattern and a green reflection with Congo red affinity. Zebrafish is an appropriate model organism for studying developmental immunology for modeling many infectious disorders. We observed that localized amyloid-like deposition was in the peritoneal membrane which is showing greenish reflection in the polarized filter with Congo red staining and immuno-positive staining with primary antibody of amyloid precursor protein. Consequently, in this case report, we demonstrated that incidentally detected and rarely seen localized amyloid-like accumulation in a zebrafish.
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10-4194-1303-2712-v20-3-07.pdf
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