Published January 1, 2013 | Version v1
Journal article Open

Concise total syntheses of (+/-)-noruleine and (+/-)-uleine

  • 1. Hacettepe Univ, Fac Educ, Dept Chem Educ, TR-06800 Ankara, Turkey
  • 2. TUBITAK Marmara Res Ctr, Chem Inst, TR-41470 Gebze, Kocaeli, Turkey

Description

The first total synthesis of (+/-)-noruleine and a concise synthesis of (+/-)-uleine have been accomplished via the DDQ mediated dehydrogenative cyclization of a tetrahydrocarbazole derivative bearing a non-substituted amide functionality to prepare the key azocino[4,3-b]indole precursor.

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