Published January 1, 2019 | Version v1
Journal article Open

Proteomic Analysis of Liver Preservation Solutions Prior to Liver Transplantation

Creators

  • 1. Acibadem Univ, Sch Med, Dept Med Biochem, Istanbul, Turkey
  • 2. TUBITAK UME Natl Metrol Inst, Gebze, Turkey
  • 3. Marmara Univ, Engn Fac, Dept Bioengn, Istanbul, Turkey
  • 4. Uludag Univ, Sch Med, Dept Gen Surg, Bursa, Turkey
  • 5. Acibadem Univ, Sch Med, Dept Gen Surg, Istanbul, Turkey
  • 6. Inonu Univ, Sch Med, Dept Gen Surg, Malatya, Turkey
  • 7. Acibadem Univ Istanbul, Vocat Sch Hlth Serv, Istanbul, Turkey
  • 8. Medipol Univ, Regenerat & Restorat Med Res Ctr, Istanbul, Turkey
  • 9. Erciyes Univ, Sch Med, Dept Med Biochem, Kayseri, Turkey

Description

Objective: Transplantation is the preferred treatment for patients with end-stage liver diseases. However, in clinical practice, functional preservation of the liver is a major concern before the transplantation. Although various protective solutions are used (in combination with hypothermia), the functional preservation time for liver is still limited to hours. We analyzed the preservation medium to detect the proteins released from the liver during storage period.

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