Published January 1, 2014
| Version v1
Journal article
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Hepatitis B virus e antigen (HBeAg) may have a negative effect on dendritic cell generation
Creators
- 1. TUBITAK Marmara Res Ctr, Genet Engn & Biotechnol Inst, TR-41470 Gebze, Kocaeli, Turkey
- 2. Istanbul Medipol Univ, Dept Med Biochem, Sch Med, TR-34083 Unkapani, Fatih Istanbul, Turkey
Description
Hepatitis B virus (HBV) continues to be a serious worldwide health problem despite the use of protective HBV vaccines and therapeutic regimens against chronic HBV infection. Chronic HBV patients cannot induce sufficient immune responses against the virus. HBV and its antigens are believed to suppress immune responses during chronic infection. Hence, studying the role of HBV in immune suppression is very important for the development of alternative therapeutic strategies for HBV infections.
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