Yayınlanmış 1 Ocak 2017 | Sürüm v1
Dergi makalesi Açık

Biophysical characterization of quaternary pyridinium functionalized polynorbornenes for DNA complexation and their cellular interactions

  • 1. TUBITAK Marmara Res Ctr, Genet Engn & Biotechnol Inst, Gebze 21, TR-41470 Gebze, Turkey

Açıklama

Cationic polymers with hydrophobic side chains have gained great interest as DNA carriers since they form a compact complex with negatively charged DNA phosphate groups and interact with the cell membrane. Amphiphilic polyoxanorbornenes with different quaternary alkyl pyridinium side chains with ethyl- p(OPy2) and hexyl unitsp(OPy6) bearing 10 kDa MWT were synthesized by living Ring- Opening Metathesis Polymerization method.

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bib-0d6ce2a0-cb47-462c-b298-be931eef48c6.txt

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md5:a1257203b3b5b16a563743524b311a1c
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