Yayınlanmış 1 Ocak 2012 | Sürüm v1
Dergi makalesi Açık

Therapeutic effects of Mycobacterium phlei cell wall extracts

  • 1. Hacettepe Univ, Fac Med, Dept Med Biochem, TR-06100 Ankara, Turkey
  • 2. Hacettepe Univ, Fac Med, Dept Urol, TR-06100 Ankara, Turkey
  • 3. Hacettepe Univ, Dept Chem, Fac Sci, TR-06532 Ankara, Turkey
  • 4. Hacettepe Univ, Fac Med, Dept Med Microbiol, TR-06100 Ankara, Turkey

Açıklama

Aim: To investigate the cytokine-stimulating activity of several Mycobacterium phlei cell wall extracts. The bacillus Calmette-Guerin application is the gold standard treatment for some types of superficial bladder carcinoma. However, its usage is limited due to its harmful side effects. Intensive research has been carried out to find less toxic and more potent therapeutic agents for treatment. Researchers focus on M. phlei for this purpose. The cell wall extract of M. phlei is sufficient for antitumoral activity.

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