Published January 1, 2020 | Version v1
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New indole-7-aldehyde derivatives as melatonin analogues; synthesis and screening their antioxidant and anticancer potential

  • 1. Erzincan Binali Yildirim Univ, Fac Pharm, Dept Pharmaceut Chem, TR-24100 Erzincan, Turkey
  • 2. Ankara Univ, Fac Pharm, Dept Pharmaceut Chem, TR-06100 Ankara, Turkey
  • 3. Ege Univ, Fac Pharm, Dept Pharmaceut Toxicol, TR-35040 Izmir, Turkey

Description

Over the last decade, there has been substantial interest in the use of melatonin (MLT) and MLT-like compounds in the treatment of several diseases. MLT can scavenge different reactive oxygen species and can also stimulate the synthesis of antioxidant enzymes.

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