Published January 1, 2012 | Version v1
Journal article Open

Use of a Y-Tube Conduit After Facial Nerve Injury Reduces Collateral Axonal Branching at the Lesion Site But Neither Reduces Polyinnervation of Motor Endplates Nor Improves Functional Recovery

  • 1. Akdeniz Univ, Fac Med, Dept Anat, TR-07070 Antalya, Turkey
  • 2. Akdeniz Univ, Fac Med, Dept Physiol, TR-07070 Antalya, Turkey
  • 3. Univ Cologne, Dept Otorhinolaryngol, D-50931 Cologne, Germany
  • 4. Univ Cologne, Inst Anat 1, Cologne, Germany
  • 5. Akdeniz Univ, Vocat Sch Hlth, Dept Biochem, TR-07070 Antalya, Turkey

Description

BACKGROUND: Despite increased understanding of peripheral nerve regeneration, functional recovery after surgical repair remains disappointing. A major contributing factor is the extensive collateral branching at the lesion site, which leads to inaccurate axonal navigation and aberrant reinnervation of targets.

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