Published January 1, 2012
| Version v1
Journal article
Open
Upregulation of T-Cell-Specific Transcription Factor Expression in Pediatric T-Cell Acute Lymphoblastic Leukemia (T-ALL)
Creators
- 1. Istanbul Univ, Deneysel Tip Arastirma Enstitusu, Genet Anabilim Dali, Istanbul, Turkey
- 2. Istanbul Univ, Cerrahpasa Med Sch, Dept Pediat Hematol, Istanbul, Turkey
- 3. Istanbul Univ, Istanbul Sch Med, Dept Pediat Hematol, Istanbul, Turkey
- 4. Bakirkoy Matern & Childrens Hosp, Dept Pediat, Istanbul, Turkey
- 5. Minist Hlth Sisli Etfal Teaching Hosp, Dept Pediat Hematol, Istanbul, Turkey
- 6. Kocaeli Sch Med, Dept Pediat Hematol, Kocaeli, Turkey
- 7. Minist Hlth Goztepe Teaching Hosp, Dept Pediat Hematol, Istanbul, Turkey
- 8. Minist Hlth Bakirkoy Sadi Konuk Teaching Hosp, Dept Hematol, Istanbul, Turkey
Description
Objective: T-cell acute lymphoblastic leukemia (T-ALL) is associated with recurrent chromosomal aberrations and abnormal ectopic gene expression during T-cell development. In order to gain insight into the pathogenesis of T-ALL this study aimed to measure the level of expression of 7 T-cell oncogenes (LMO2, LYL1, TAL1, TLX1, TLX3, BMI1, and CALM-AF10) in pediatric T-ALL patients.
Files
10-5505-tjh-2012-13540.pdf
Files
(405.1 kB)
| Name | Size | Download all |
|---|---|---|
|
md5:eff07982051d62f525e96de87133fcae
|
405.1 kB | Preview Download |