Published January 1, 2012
| Version v1
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Effect of Oral TGF-A Formulations on ASA Induced Duodenal Ulcer and The Role of Lipid Peroxidation in The Healing Process
- 1. Gazi Univ, Fac Med, Dept Physiol, TR-06500 Ankara, Turkey
- 2. Gazi Univ, Fac Pharm, Dept Pharmaceut Technol, TR-06510 Ankara, Turkey
- 3. Gazi Univ, Dept Histol & Embriol, Fac Med, TR-06500 Ankara, Turkey
Description
Objective: This study was designed to investigate the effects of aqueous or Microemulsion solution containing Transforming Growth factors-alpha (TGF-a) and/or administration of aprotinin on healing rate of duodenal ulcer induced by acetylsalicylic acid, and to examine the relationships between oxidative processes and TGF-a formulation during duodenal ulcer healing by measuring malondialdehyde, glutathione and total nitric oxide levels.
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