Published January 1, 2012 | Version v1
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Synthesis of new di-(3-indolyl)arenes

  • 1. Univ New S Wales, Sch Chem, Sydney, NSW 2052, Australia

Description

1,4-Di-(3-indolyl)benzene 6 and 2,8-di-(3-indolyl)dibenzofuran 12 were synthesized from 1,4-diacetylbenzene and 2,8-diacetyldibenzofuran, respectively, via indole synthetic strategies. Investigation into the acid-catalysed formation of macrocyclic systems from these di-(3-indolyl)arenes led to the development of the 18-membered macrocycle 14 from the diindolylbenzene 6, which was capable of undergoing complexation with nickel(II) ions. (C) 2012 Elsevier Ltd. All rights reserved.

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