Published January 1, 2012
| Version v1
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Multilocus Microsatellite Typing (MLMT) of Strains from Turkey and Cyprus Reveals a Novel Monophyletic L. donovani Sensu Lato Group
Creators
- 1. Hellenic Pasteur Inst, Mol Parasitol Lab, Athens, Greece
- 2. Al Quds Univ, Fac Pharm, Jerusalem, Israel
- 3. Hellenic Pasteur Inst, Lab Med Microbiol, Athens, Greece
- 4. Charles Univ Prague, Dept Parasitol, Fac Sci, Prague, Czech Republic
- 5. Ege Univ, Dept Parasitol, Sch Med, Izmir, Turkey
- 6. Charite, Inst Mikrobiol & Hyg, D-13353 Berlin, Germany
Description
Background: New foci of human CL caused by strains of the Leishmania donovani (L. donovani) complex have been recently described in Cyprus and the C, ukurova region in Turkey (L. infantum) situated 150 km north of Cyprus. Cypriot strains were typed by Multilocus Enzyme Electrophoresis (MLEE) using the Montpellier (MON) system as L. donovani zymodeme MON-37. However, multilocus microsatellite typing (MLMT) has shown that this zymodeme is paraphyletic; composed of distantly related genetic subgroups of different geographical origin. Consequently the origin of the Cypriot strains remained enigmatic.
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